Infrastructure AI Startup Jobs

Unified analytics platform for data and AI, helping companies process and analyze big data in the cloud.

Defense technology company building autonomous systems and AI-powered defense capabilities to transform military and border security operations.

AI research company creating safe AGI that benefits all of humanity, known for ChatGPT and GPT models.

AI safety company building reliable, interpretable, and steerable AI systems, creator of Claude.

Defense AI company building autonomous aircraft and AI pilot technology for military applications.

Airwallex is a venture-backed fintech building cross-border payments and global financial infrastructure for businesses operating internationally. It offers multi-currency business accounts, global payments, cards, and embeddable money-movement APIs, and is expanding into AI-native and agentic finance products. The company runs dual global headquarters (Singapore and San Francisco) with a significant US presence and hiring footprint.

Crusoe builds renewable-powered AI infrastructure, including cloud, data center, and manufacturing capabilities designed for large-scale AI workloads.

Canonical is the company behind Ubuntu, the world's most widely used Linux distribution, and provides commercial support, cloud infrastructure tools, and enterprise open-source software services. It is privately held and self-funded by founder Mark Shuttleworth, with no external venture funding rounds, and continues to expand partnerships such as its 2025 collaboration with Broadcom.

CesiumAstro builds communications systems and phased-array hardware/software for space, air, and ground missions, supporting satellite and defense connectivity use cases.

Cyera is an AI-native data security platform that helps enterprises discover, classify, govern, and protect sensitive data across cloud, SaaS, on-premises, and AI environments. The platform uses machine learning and LLMs for high-precision data classification at scale.

Cloud infrastructure platform providing affordable GPU compute for AI workloads and model training.

VAST Data is an AI data platform company that provides a unified storage, database, and data management operating system designed to capture, enrich, and serve massive datasets for AI and enterprise workloads at scale.

Flexport is a technology-enabled freight forwarding and supply chain logistics platform that combines software, data, and operational services to help businesses manage global trade and freight movement. The company offers ocean and air freight, customs brokerage, trucking coordination, and fulfillment solutions for over 13,000 companies across more than 147 countries.

Form Energy develops iron-air battery technology for multi-day, utility-scale energy storage, with R&D and engineering in Somerville, MA and Berkeley, CA and a manufacturing plant (Form Factory 1) in Weirton, WV. The company has raised over $1.2B across multiple rounds including a $405M Series F in October 2024.

Base Power is building America's next-gen power company by deploying whole-home battery backup systems that protect families from outages and strengthen the grid. Deployed over 100MWh of residential battery capacity.

Vast is a US-based commercial space company building human-rated artificial-gravity orbital space stations, starting with its single-module Haven-1 station targeted as the world's first commercial space station. Founded by Jed McCaleb and headquartered in Long Beach, California ('Space Beach'), the company designs and manufactures its spacecraft hardware in-house. It is racing to provide a commercial successor to the International Space Station.

Data infrastructure company providing high-quality training data for AI applications, recently partnered with Meta.

Fivetran builds automated ELT data pipelines with 700+ pre-built connectors that move data from SaaS apps, databases and files into cloud warehouses and lakehouses. In October 2025 it completed an all-stock merger with dbt Labs, adding data transformation and modeling to its movement layer for a combined entity approaching $600M ARR. Headquartered in Oakland, CA, it remains private and is the surviving brand with co-founder George Fraser as CEO.

Atoms is Travis Kalanick's physical-AI and industrial robotics holding company, rebranded in March 2026 from City Storage Systems. It operates business units across food (CloudKitchens, Otter, Lab37, Picnic), autonomous mining (built on acquired robotics firm Pronto), and transport, building a shared robotics 'wheelbase' for specialized industrial machines rather than humanoids. The company runs operations in 110+ cities and raised $1.7B led by a16z in July 2026, with Ben Horowitz joining the board.

Defense technology company building unmanned defense systems and distributed manufacturing.

ElevenLabs is the leading AI voice technology platform, offering ultra-realistic text-to-speech, voice cloning, and audio AI tools used by content creators, enterprises, and developers worldwide. The company has grown to over $330M in annual recurring revenue and serves customers across 45+ countries including Deutsche Telekom and Revolut.

Apex is a defense-grade satellite bus manufacturer producing configurable, productized spacecraft platforms (Aries, Nova, Comet) for LEO, MEO, and GEO orbits. The Los Angeles-based company serves commercial and sovereign government customers at scale with peak annual capacity exceeding 200 units per year. Apex launched Project Shadow, the first commercially-led on-orbit space-based interceptor demonstration.

Redwood Materials builds a circular supply chain for lithium-ion batteries, recycling end-of-life batteries and production scrap, refining critical elements like lithium, nickel, and cobalt, and manufacturing battery materials domestically. It also deploys large-scale energy storage systems using second-life EV battery packs. Founded by former Tesla CTO JB Straubel, it operates facilities in Nevada and South Carolina.

Commonwealth Fusion Systems is an MIT spinout developing commercial fusion energy, building the SPARC demonstration tokamak in Devens, MA and the ARC commercial power plant in Virginia. It has raised roughly $4 billion to date, including a $1 billion round in July 2026 from pension funds, sovereign wealth funds, and infrastructure investors.

General Matter is rebuilding domestic uranium enrichment capacity in the U.S., developing low-enriched and high-assay low-enriched uranium to support advanced nuclear power and American energy security.

Hadrian builds AI-enabled autonomous factories that manufacture precision components and systems for aerospace, defense, shipbuilding, and other industrial customers, combining software, robotics, machining, inspection, and factory operations.

Autonomous penetration testing platform that continuously discovers and exploits attack paths.

Plaid provides a financial data API infrastructure that lets applications securely connect to users' bank accounts for payments, lending, and personal finance use cases. Headquartered in San Francisco with offices in Seattle and NYC, it is a fintech unicorn preparing for a potential IPO.

Tenstorrent designs AI accelerator chips and RISC-V processors, building both hardware and software for high-performance machine learning workloads. Founded by CEO Jim Keller, it has offices in Austin, Santa Clara, and Toronto.

Company behind the open-source Grafana observability stack providing monitoring, logging, and tracing solutions, reaching $400M ARR as a fully remote company across 40+ countries.

Cato Networks develops a cloud-native Secure Access Service Edge (SASE) platform that converges SD-WAN, SSE, ZTNA, and FWaaS into a single global service. Founded in Tel Aviv in 2015 by Shlomo Kramer and Gur Shatz, it serves over 1,000 enterprise customers and is a cybersecurity unicorn valued above $4.8B.

Cohere builds foundational AI models and enterprise solutions for search, generation, and agentic workflows. Their platform includes Command, Embed, Rerank, and the North agentic AI suite, enabling businesses to deploy secure, production-grade AI on private or sovereign infrastructure.

Nuro develops autonomous driving technology and licenses its Nuro Driver platform to automotive and mobility partners for commercial deployment.

Etched is an American semiconductor startup building Sohu, an ASIC purpose-built for transformer inference rather than general-purpose GPU compute. The company co-designs chips, racks, system software and manufacturing into full frontier inference clusters optimized for both prefill and decode workloads. Founded by Harvard dropouts in 2022, it raised a $300M Series C in July 2026 at a $10.3B valuation to scale production against Nvidia.

Radiant is pioneering mass-produced portable nuclear microreactors, with its flagship Kaleidos reactor delivering 1 MW of clean, zero-emission power in a shipping container-sized form factor. Valued at $1.8 billion, the company is building its factory in Oak Ridge, Tennessee.

Nuclear energy innovation company developing advanced reactor prototypes using silicon carbide technology for next-generation nuclear power

Figure develops general-purpose humanoid robots and embodied AI systems for industrial and logistics environments, combining robotics hardware with AI control systems.

LangChain provides open-source frameworks and a managed platform (LangSmith, LangGraph) for building, observing, and deploying LLM-powered applications and agents. Its composable, modular components let developers integrate large language models into production workflows. Backed by Sequoia and IVP, LangChain is the leading developer framework for agentic AI.

1X Technologies builds general-purpose humanoid robots designed for home and industrial use. Their flagship products include EVE for industrial facilities and NEO for the home. Backed by OpenAI.

TerraPower develops advanced nuclear reactor technology, including its Natrium sodium-cooled fast reactor with integrated molten salt energy storage, and an isotope production business for cancer treatment. Founded by Bill Gates and based in Bellevue, WA, it is building its first commercial Natrium unit with U.S. Department of Energy support.

Ripple provides enterprise-grade crypto payments, custody, and stablecoin infrastructure, enabling banks and financial institutions to move money globally using blockchain technology. Based in San Francisco, it is one of the most valuable private crypto companies with a $40B valuation.

Cloud platform for frontend teams building with Next.js and modern web frameworks, offering global edge infrastructure.

Platform for deploying and scaling machine learning models in production.

AI infrastructure company providing cloud GPUs, GPU clusters, private cloud, and hardware systems for AI training and inference workloads.

Real-time public safety data platform for law enforcement and first responders.

Antares is developing mass-producible, inherently safe nuclear microreactors for terrestrial, underwater, and space-based applications, producing between 100 kilowatts and 1 megawatt of electricity. The company has a 145,000-square-foot manufacturing facility in Torrance, California and is on track to achieve first reactor criticality by mid-2026. Founded by alumni of SpaceX, MIT, and Los Alamos National Lab, Antares is backed by over $130 million in venture capital and government funding.

Enterprise voice AI platform offering Speech-to-Text, Text-to-Speech, and Voice Agent APIs for real-time and batch use, deployable in cloud or self-hosted.

Kong Inc. provides an open-source API gateway, service mesh, and API management platform that lets developers connect, secure, and observe APIs and microservices across hybrid and multi-cloud environments. Its Konnect SaaS platform extends this into unified API lifecycle management and, more recently, connectivity for AI applications. Founded in 2009, Kong is a widely adopted developer-infrastructure company.

Fireworks AI runs an inference and fine-tuning platform for open-source generative AI models. Developers and enterprises use its API to serve models at low latency and high throughput. It was founded in 2022 by former Meta PyTorch and Google engineers.

Cloud email security platform using AI to detect and prevent sophisticated email attacks.

Inversion Space is turning space into a transportation layer for Earth by building autonomous re-entry vehicles that enable precision delivery of cargo to anywhere on the planet in under an hour, creating an on-demand logistics network in Low-Earth Orbit.

Vanta provides an AI-powered Trust Management Platform that automates compliance, security, and risk management for businesses. The company helps organizations earn and prove trust through automated security monitoring and compliance frameworks.

Waabi develops AI-first autonomous trucking software and simulation systems to accelerate validation and deployment of self-driving transport technology.

Founded by Robinhood co-founder Baiju Bhatt, Cowboy Space (formerly Aetherflux) builds vertically-integrated rockets and solar-powered orbital data centers to run AI/GPU compute workloads in low Earth orbit. The company pivoted from space-based solar power to orbital data centers, determining that building its own rockets was necessary to scale the economics.

Full-stack AI engineer that lets anyone build complete web applications with plain English, transforming raw ideas into production-ready software with front-end and back-end functionality.

Together AI provides an AI-native cloud platform for inference, fine-tuning, GPU clusters, and large-scale model training, helping AI engineers and researchers build and scale open-source and enterprise AI systems.

Delivers secure container images and tooling to protect open-source supply chains by default.

Neutral-atom quantum computing systems and software.

1Password provides password, secrets, and access management software for teams and enterprises, securing credentials, app access, and AI tool usage in one platform.

Northwood Space designs and manufactures electronically steered phased-array ground stations that enable scalable, rapidly deployable satellite communication and tracking infrastructure. The company serves commercial and government customers including a $50M U.S. Space Force contract to modernize the Satellite Control Network.

Aircall is a cloud-based call center and CCaaS platform that enables businesses to set up and manage phone support operations integrated with CRM, helpdesk, and productivity tools. Founded in 2014 in Paris, the company reached unicorn status in 2021 with a $1B+ valuation and reported $204M ARR. It serves over 85,000 customers globally.

Data pipeline platform that gives you control over your observability data.

Jeeves is a global financial infrastructure platform providing corporate cards, expense management, cross-border payments, and bill pay for businesses operating across 25+ countries. Founded in 2019 and valued at $2.1B, Jeeves enables companies to spin up their finance function within minutes.

Stoke Space Technologies develops the fully and rapidly reusable Nova rocket designed to operate with aircraft-like frequency. Founded by former Blue Origin and SpaceX employees, raised over $1.3B.

Metropolis builds AI and computer-vision infrastructure for checkout-free parking and payments, operating as the largest parking operator in North America after acquiring SP Plus. The company is expanding its 'Recognition Economy' platform beyond parking into retail, hospitality, and fueling verticals.

API-first stock/ETF/crypto brokerage infrastructure for developers.

Temporal provides a durable execution platform that enables developers to build reliable, fault-tolerant distributed applications. The open-source workflow orchestration engine ensures long-running processes and agentic AI workloads run to completion even in the face of failures.

Develops factory-fabricated modular nuclear microreactors designed for AI data centers and industrial applications. The Aalo Pod is a 50 MWe power plant purpose-built for data centers.

Agentic software creation platform enabling anyone to build applications using natural language with collaborative browser-based IDE

The Nuclear Company operates as America's deployment platform for nuclear power, constructing a series of nuclear power plants using a design-once, build-many approach with proven and licensed technology to deliver safe and reliable electricity at the lowest cost.

TensorWave provides AMD-powered AI infrastructure and cloud GPU clusters for large-scale training and inference workloads.

Genesis AI is building a universal foundation model for robotics, training on large-scale synthetic physical-world data for research and production systems.

SambaNova Systems designs AI inference chips, systems, and cloud services for enterprise and government customers. The company builds full-stack AI infrastructure including its Reconfigurable Dataflow Unit (RDU) chips and SambaNova Cloud inference platform.

Saviynt builds enterprise identity security and governance software, offering a cloud-native platform that secures human, machine, and AI-agent identities across cloud and business systems. The company is headquartered in El Segundo, California, and was founded in 2010.

Vertically integrated home electrification company deploying affordable all-electric heat pump systems across North America, reducing upgrade costs up to 50% with over 1,000 installations to date

Vultr offers global cloud compute services, providing high-performance, cost-effective virtual servers and GPUs for developers and businesses.

Bedrock Robotics brings autonomy to construction equipment, deploying AI systems that operate heavy machinery on real job sites to accelerate infrastructure work.

WEKA builds a cloud and AI data platform that accelerates model training and inference workloads with high-performance, software-defined storage.

Mecka AI is a Toronto- and New York-based startup that collects and analyzes human motion data, captured via smartphones and body sensors, to train humanoid and other robots. It positions itself as a data and deployment layer for physical AI, akin to what Scale AI, Mercor, and Surge provide for LLMs, and also deploys robots commercially for enterprise customers.

AI research lab founded by former OpenAI CTO Mira Murati, building Tinker, an API for distributed LLM fine-tuning that makes model customization accessible without massive GPU infrastructure.

Embeddings-based search infrastructure providing a meaning-aware search API for AI applications. Exa trains embedding models to convert web pages into vector representations, enabling semantic search that understands intent rather than just matching keywords.

Supabase is an open-source Firebase alternative providing a full backend-as-a-service platform built on PostgreSQL, including database, auth, realtime subscriptions, edge functions, storage, and vector embeddings for developers.

Sentry is an application monitoring platform that helps developers diagnose, fix, and optimize the performance of their code. It provides error tracking, performance monitoring, and session replay across 100+ languages and frameworks.

TAR builds self-contained, off-grid renewable power and battery systems for AI data centers, deploying at gigawatt scale without relying on the electrical grid. Founded in 2026 by Pat Becker and Leonhard Soenke, the company is headquartered in Austin with engineering in San Francisco and manufacturing in West Texas.

Clear Street is a cloud-native clearing, custody, and brokerage platform built to modernize capital markets infrastructure. It serves institutional clients including hedge funds, family offices, and ETF issuers across equities, options, futures, and fixed income.

Reflection AI is building frontier open intelligence accessible to all, developing open-weight AI models. Founded by former Google DeepMind researchers who co-created AlphaGo, raised $2B at an $8B valuation.

Snorkel AI provides a data-centric AI platform for building specialized AI systems, helping enterprises and frontier teams create, curate, evaluate, and govern expert data for production models and agents.

Velaura AI (formerly Auradine) designs ultra-low-power silicon, systems, and IP for AI accelerators, data centers, and physical AI applications like robotics and autonomous systems. Its Titan Core platform targets 2-4x better performance per watt for AI compute infrastructure.

Overland AI develops autonomous ground vehicle software and systems for off-road and contested environments, with defense-focused robotics deployments.

Dash0 is building the first AI-native observability platform powered by Agent0, an SRE AI agent that helps developers and operators quickly identify and fix application and infrastructure issues, processing millions of data points with OpenTelemetry-native architecture.

Mollie is a European payment service provider offering a simple, developer-friendly API for online payments, subscriptions, and financial services. It supports a wide range of payment methods across Europe, serving tens of thousands of businesses from startups to enterprises.

Builds digital in-memory compute hardware and software stack for low-latency, energy-efficient LLM inference.

Fastest generative media platform for developers providing access to 1,000+ production-ready AI models for image, video, audio, and 3D generation through a unified API and serverless GPU infrastructure.

Meter provides enterprise network infrastructure as a managed service, bundling hardware, software, and operations for office connectivity and security.

PhysicsX is an AI company accelerating industrial innovation by combining AI-driven multiphysics inference with numerical simulation to improve the design, manufacturing, and operation of complex products. Founded in 2019 by former Formula 1 engineers, the platform serves enterprises across aerospace, defense, automotive, semiconductors, and energy sectors. PhysicsX raised over $155M including investments from NVIDIA, Atomico, and Temasek.

Edge computing company providing modular data centers and connectivity platforms to deliver cloud and AI capabilities to remote environments.

Encord is a data development platform for AI that helps teams curate, manage, and label training data at scale. The company serves 300+ AI teams including Toyota and Skydio, processing over 5PB of data.

Epirus is a defense technology company that builds software-defined high-power microwave and directed-energy systems for counter-UAS, counter-swarm, and electronic-warfare missions. Its flagship Leonidas platform disables drones and electronic threats using solid-state, software-updatable hardware, and the U.S. Army has selected it for its Indirect Fire Protection Capability program.

n8n is a fair-code workflow automation platform that enables technical teams to build complex automations with the flexibility of code and the speed of no-code, supporting 400+ integrations and self-hosted or cloud deployment.

Tailscale builds identity-first networking software on WireGuard so teams can securely connect users, devices, services, and AI systems across private infrastructure without VPN complexity.

Supply chain intelligence platform using AI to provide global value chain transparency for enterprises and governments.

Serverless cloud platform for developing, deploying, and scaling AI applications. Developers can run any code in the cloud without managing infrastructure, with built-in support for GPU workloads and batch jobs.

Everlaw is a cloud-native legal technology company providing an ediscovery and litigation platform for law firms, corporations, and government agencies. Its software uses AI and machine learning to accelerate document review, evidence analysis, and case-building workflows. Founded in 2010 and based in Oakland, California.

Mytra develops automated robotic storage and warehouse automation solutions using bots, software, and modular cells. The platform features AI-optimized dynamic pathways, slotless inventory management, and a three-dimensional grid system for storing and moving materials in warehouses. Founded by ex-Tesla and Rivian leaders.

7AI builds an agentic cybersecurity platform that uses swarming AI agents to automate SOC investigations and response workflows.

Eon is the first cloud backup posture management (CBPM) platform, automating and unifying complex cloud backups into a queryable data lake for fast recovery, compliance, and AI analytics. Founded by the team behind AWS Disaster Recovery, Eon converts idle backup data into an accessible secondary storage layer for enterprise AI workloads.

Gigs provides telecom infrastructure and APIs that let companies launch branded mobile services, phone plans, and connectivity products without becoming carriers.

Building vertically integrated, automated metal factories in Detroit that deliver raw materials faster, cheaper, and more reliably to US manufacturers. Software-driven quoting in milliseconds.

Omni is a modern business intelligence and analytics platform that combines a unified semantic data model with SQL flexibility, enabling AI-powered trustworthy answers in seconds. The platform supports embedded analytics, custom dashboards, and governed data exploration.

Robotics AI company building foundation models for general-purpose robots to handle physical world interactions with advanced manipulation capabilities

Building America's next generation of power infrastructure with hybrid inertial-battery systems combining mechanical flywheels with battery duration, providing grid stabilization without combustion or chemicals.

Array Labs builds high-power, low-cost space radar systems and a formation-flying radar constellation for large-scale 3D Earth imaging and persistent monitoring.

Prime Intellect is an AI infrastructure company that enables training and deploying frontier AI models across decentralized, globally distributed compute resources, commoditizing both compute and intelligence for researchers and organizations.

Unified observability platform for hardware sensor data

Yuno is a global payment orchestration platform that connects enterprise merchants to over 1,000 payment methods, processors, and fraud prevention tools through a single API. Its AI-driven smart routing maximizes authorization rates and reduces processing costs for brands like McDonald's, Uber, Rappi, and inDrive.

H Company is a frontier AI company building autonomous agents and foundation-model systems for enterprise work. The company develops research, model, inference, and infrastructure capabilities behind products like Runner H.

Periodic Labs is an AI research company focused on building autonomous AI scientists and software systems that accelerate scientific discovery.

Render provides cloud infrastructure for developers to deploy, run, and scale applications, databases, static sites, and AI workloads.

Tines provides an intelligent workflow and orchestration platform that lets security, IT, and operations teams automate complex actions, investigations, and AI-assisted processes without heavy custom code.

Application security and software supply chain security platform for modern DevSecOps.

Firecrawl is a web data infrastructure platform that converts websites into clean, structured data optimized for AI applications through a simple API, turning entire websites into LLM-ready markdown or structured data.

incident.io is an incident management platform used by over 1,000 companies including Netflix, Airbnb, and Block to manage hundreds of thousands of incidents. The platform integrates with Slack for real-time coordination and builds AI agents that help resolve incidents autonomously.

TerraFirma is an Austin-based, vertically integrated construction robotics company founded in 2024 by former SpaceX engineers Noah Schochet (CEO) and Noah McGuinness (CTO). It retrofits heavy equipment — excavators, dozers, loaders, rollers, skid steers — for AI-assisted remote and semi-autonomous operation, paired with AI construction planning software. Rather than only selling robots to contractors, TerraFirma takes on earthwork, demolition, site prep, and infrastructure projects itself for data centers, roads, substations, and energy sites.

Vega offers a lightweight, AI-native security analytics fabric that provides instant access to all data sources without requiring migration, designed to replace traditional SIEM solutions with state-of-the-art security analytics for modern enterprises.

Mapbox is a location data platform that provides custom maps, geocoding, navigation, and search APIs for developers and enterprises. It serves customers across automotive, mobility, and consumer apps, with growing focus on AI-powered location intelligence and in-car assistants.

Designs and fabricates superconducting quantum processors at industrial scale using its open VIO architecture, serving 50+ customers across 20 countries.

Smart panel provider for home energy management enabling intelligent control and optimization of household energy consumption

KoBold Metals is a Berkeley, California-based mineral exploration company that uses AI, machine learning, and geoscience data fusion to discover critical mineral deposits (copper, nickel, cobalt, lithium) needed for the energy transition. Founded in 2018, it is behind the large Mingomba copper discovery in Zambia and is backed by investors including a16z, Breakthrough Energy, T. Rowe Price, and BHP.

Partly provides infrastructure and APIs for the auto parts industry, standardizing communication protocols and enabling automation across the supply chain for repairers, OEMs, and green suppliers.

Defense technology company building AI-powered software for national security missions.

Brain Co. is a San Francisco company building agent-native operating systems for large institutions in the public and private sectors. It delivers custom AI platforms and applications — combining LLMs, machine learning, rule engines, and workflow automation — for enterprises and government organizations across permitting, supply chain, healthcare, and energy. Co-founded in 2024 by Jared Kushner, Elad Gil, Luis Videgaray, and Eric Wu, it works with 10+ Global 2000 customers and has a strategic partnership with OpenAI.

Provides unified SDK and tools for connecting AI agents to SaaS APIs and secure credentials.

Gruve delivers AI-native infrastructure, inference systems, and enterprise AI agents for inference-heavy workloads with an emphasis on speed, security, and measurable outcomes.

Doppel provides AI-powered digital risk protection that combines brand protection, executive protection, social engineering simulation, and awareness tooling to detect and disrupt impersonation, phishing, and other online threats.

Fuse Energy Technologies builds pulsed-power machines (Marx generators like TITAN) for magnetized liner inertial fusion (MagLIF), generating near-term revenue from nuclear-effects radiation testing for the NNSA, national labs, and defense agencies while working toward commercial fusion power. Founded in 2019 by JC Btaiche and headquartered in San Leandro, CA.

Roboflow provides end-to-end computer vision tools that enable developers and enterprises to build, deploy, and manage vision AI models. The platform supports the full lifecycle from data labeling and model training to inference deployment, serving over 250,000 developers and powering applications across industries including manufacturing, retail, and agriculture.

WorkOS is a developer platform that provides APIs for quickly adding enterprise-grade features like Single Sign-On (SSO), Directory Sync (SCIM), Audit Logs, and User Management to applications. Often described as 'Stripe for enterprise features,' WorkOS powers authentication and identity for the fastest-growing AI companies including OpenAI, Anthropic, and Cursor.

Alice & Bob is a Paris-based quantum computing startup building the first universal, fault-tolerant quantum computer using cat qubits with built-in error correction. The company has developed a roadmap to 100 logical qubits by 2030.

Flock Safety builds AI-powered cameras and software that help law enforcement and communities solve and prevent crime. The platform uses machine learning and computer vision to provide investigative intelligence for cities, neighborhoods, and businesses.

Function Health offers a membership-based health platform that gives consumers access to 100+ lab tests, clinician-reviewed insights, and longitudinal health tracking to detect risk earlier and manage wellness proactively.

Island builds the Enterprise Browser, a Chromium-based browser that embeds security, governance, and productivity controls directly into the browsing experience for organizations. It has expanded into an agentic control plane that governs how both employees and AI agents access corporate applications, networks, and data.

Quantum and AI company developing solutions for drug discovery, cybersecurity, and navigation.

Traversal builds AI-powered site reliability engineering agents that investigate incidents, triage alerts, and automate infrastructure remediation.

LiveKit is an open-source infrastructure platform for building realtime voice, video, and AI agent applications. Their platform powers products like OpenAI's ChatGPT Voice Mode, serving over 200,000 developers with billions of calls per year.

RunPod is a GPU cloud infrastructure provider that enables developers, researchers, and AI companies to deploy and scale GPU workloads on demand. The platform offers serverless inference, on-demand GPU pods, and instant multi-node clusters, serving over 500,000 developers.

Nexthop AI builds networking systems for AI-scale data centers, focusing on high-performance switching infrastructure for hyperscale and cloud environments.

Privacy-first mobile carrier redesigning telecommunications from the ground up. Cape owns and operates its own mobile core and SIMs, providing ultra-private and secure connectivity for enterprises, government, and consumers.

Developing analog in-memory compute chips and software for energy-efficient AI at the edge.

Retool builds an enterprise application platform for creating internal tools, workflows, and AI agents on top of existing databases, APIs, and business systems.

Torq builds a hyperautomation platform for security operations teams, connecting detections, investigations, and response workflows so analysts can automate repetitive SOC work across tools.

Embedded credit card platform enabling businesses to launch and manage integrated credit card experiences. Partners include Coinbase, Bilt, Qatar Airways, and Alibaba.

Lunar Energy builds home energy systems and software that integrate batteries, solar, and grid services for households and utilities.

Mythic builds power-efficient analog compute technology for AI inference, targeting edge-to-enterprise deployments where energy efficiency and throughput are critical.

Pacific Fusion is building a high-gain pulsed magnetic fusion system designed to achieve net facility gain, delivering more fusion energy output than all stored energy input. The company develops affordable, modular fusion technology using common materials to provide abundant, clean energy for a prosperous planet.

Primer builds payment orchestration infrastructure for online merchants, giving teams a no-code workflow layer to connect processors, optimize routing, and manage the full payment stack through one integration.

Watney builds dual-armed robots that perform physical maintenance work inside hyperscale AI data centers, such as cable swaps and server restarts. Founded in San Francisco in 2023 by Ryan Gannon and Sean Cheong, it has been testing robots with Meta since 2025 and operates the largest fleet of dexterous robots running 24/7/365 across the United States.

Cartesia builds real-time voice and multimodal AI models with low-latency inference for production applications. Its platform combines foundational model research with developer APIs for voice agents, audio generation, and on-device intelligence.

Efficient Computer builds the world's most energy-efficient general-purpose processor, the Electron E1, offering up to 100x greater efficiency than traditional CPUs. Spun out of Carnegie Mellon University, their Fabric architecture minimizes data movement, enabling applications in AI, edge computing, space, defense, and consumer devices.

Fingerprint provides device intelligence APIs that help teams recognize returning visitors, prevent fraud, secure accounts, and reduce abuse across web and mobile products.

NODA AI is an AI-native defense company building autonomy orchestration software that enables command and control of mixed autonomous and manned assets across multi-domain military operations. Its platform serves as a vendor-agnostic reasoning layer coordinating heterogeneous autonomous systems for the Department of Defense and allied defense customers.

Normal builds AI systems and thermodynamic computing hardware to accelerate semiconductor design and improve energy efficiency in compute. The company works with large chip and manufacturing partners while developing its own next-generation computing architecture.

Tive delivers real-time shipment visibility with sensor hardware and cloud software, helping teams monitor location and condition to reduce logistics risk and loss.

Upscale AI provides high-performance networking solutions for AI infrastructure. The company delivers open-standard connectivity for specialized computing, making AI more accessible through ready-to-use networking platforms designed for next-generation AI workloads.

Zeta is a next-generation banking technology company providing cloud-native, fully stackable card processing and core banking platforms for banks and fintechs. Its Tachyon platform powers credit, debit, and prepaid card issuance, lending, and digital banking experiences for issuers. Over 25 million cards run on Zeta-powered platforms across 7 countries, supported by 1,700+ employees.

A robotics company providing robotic solutions for wind turbine blade maintenance and inspection, using specialized robots for cleaning, coating, and repair.

Artemis is an AI-native cybersecurity platform that builds a living model of an organization's identities, devices, cloud, and SaaS environment to detect, investigate, and autonomously respond to AI-powered attacks. The company emerged from stealth in April 2026 with $70M in combined seed and Series A funding led by Felicis, and counts Mercury, Wix, Lemonade, and Abnormal AI among its customers.

Fundamental builds large tabular models and enterprise AI infrastructure for prediction and analysis on complex business data, focused on tabular reasoning and decision support.

Parallel builds web infrastructure for AI agents, providing APIs and tooling that let models search, browse, and interact with the live web more reliably.

Vertically integrated electrical wire harness manufacturing platform for complex industrial supply chains.

Amenitiz offers an all-in-one hotel management platform for independent hoteliers, including booking, payments, and operations tools.

Builds Large Physics Models that use AI to simulate atmospheric behavior for faster weather forecasting, producing predictions in minutes rather than hours via traditional supercomputers.

CoLab Software builds an AI-powered Design Engagement System (EngineeringOS) that helps mechanical and hardware engineering teams collaborate on CAD designs, conduct design reviews, and apply AI-driven checks (AutoReview) to accelerate product development. Customers include Johnson Controls and Ford. The platform turns every review into a structured, searchable knowledge base for engineering teams.

Column is a nationally chartered bank building developer-first banking infrastructure. It offers APIs and software for payments, ledgers, compliance, and bank programs so fintech companies can build on regulated banking rails.

Domino Data Lab provides an enterprise AI and MLOps platform for model development, deployment, governance, and compliance. Trusted by over 20% of the Fortune 100, the platform helps data science and machine learning teams manage regulated model workflows at scale. The company has rebranded to Domino and is backed by Sequoia Capital, Coatue, Great Hill Partners, and Highland Capital Partners.

Generalist AI is building embodied foundation models for general-purpose robots, starting with a focus on dexterous manipulation, leveraging research from OpenAI, Boston Dynamics, and Google DeepMind to create end-to-end deep neural networks that map sensor data to real-time robotic actions.

Network infrastructure management platform based on open-source NetBox for enterprise automation.

Intelligent terminal for developers with AI-powered features, built with Rust to supercharge developer productivity through Agent Mode for seamless code generation, editing, and task management.

Robotics company using wall-climbing robots and AI for industrial inspections and predictive maintenance.

Kepler Communications is a Toronto-based satellite connectivity operator building a global low-Earth orbit constellation for broadband and IoT connectivity. The company deploys optical inter-satellite links and is expanding into orbital AI compute via Nvidia Orin chips. Founded in 2015, Kepler has raised over $177M to connect space-borne and ground assets worldwide.

Neurophos is an Austin-based semiconductor startup developing photonic AI inference chips, spun out of metamaterials research at Duke University. Its Optical Processing Unit (OPU) compresses rack-scale AI compute into a single package using CMOS-compatible photonic tensor cores, targeting the compute-bound prefill stage of inference.

Paxos is a regulated blockchain infrastructure company that issues stablecoins and builds financial market infrastructure for tokenization, settlement, and custody. It powers crypto brokerage services for partners like PayPal and Venmo and operates as a chartered trust company under NYDFS, Singapore MAS, and Abu Dhabi FSRA.

Builds open-source frontier AI infrastructure including SGLang, the fastest LLM inference engine, and large-scale RL training frameworks.

Skyryse develops SkyOS, a universal operating system for flight, and is bringing software-defined avionics and autonomy to existing and new aircraft platforms.

Tomorrow.io delivers weather intelligence software and proprietary weather data products for aviation, defense, logistics, and enterprise operations.

Alchemy is a blockchain developer platform providing infrastructure, APIs, and tooling for building Web3 and on-chain applications, powering node access, scaling, and analytics for developers. Founded in 2017 by Stanford alumni Nikil Viswanathan and Joe Lau, it is headquartered in San Francisco with an additional office in New York.

Arena (formerly LMArena) operates a crowdsourced AI model evaluation platform where users compare and vote on outputs from different large language models, producing public Elo-based leaderboards. Founded by UC Berkeley researchers, it now serves enterprises evaluating AI model performance in production.

Company behind Astro, a managed Apache Airflow DataOps platform for data & AI pipelines.

Atomic Industries is an AI-powered tool-and-die manufacturer that applies machine learning to modernize precision manufacturing.

Matic is the world's most advanced floor cleaner, a fully autonomous robot vacuum that continuously scans the perimeter of your home with high-resolution cameras, LiDAR, radar, and thermal sensors for comprehensive cleaning.

Mesh builds crypto payments infrastructure that lets merchants and fintech platforms accept digital assets while settling instantly in stablecoins.

Oratomic is a Pasadena-based, Caltech-spun-out startup building the world's first fault-tolerant, utility-scale quantum computer using reconfigurable neutral-atom arrays manipulated by optical tweezers. Founded in 2026 by Dolev Bluvstein and Manuel Endres, it aims to skip intermediate NISQ products entirely.

River AI is a Palo Alto–based AI startup founded by former xAI co-founder Igor Babuschkin, building a full-stack platform for custom, open-weight model development. Its API lets developers fine-tune open models with reinforcement learning and LoRA, completing complex RL training runs in 15–20 minutes without dedicated infrastructure. The company positions itself as an alternative to prompt engineering against closed-source incumbents.

Runlayer is the enterprise control plane for Model Context Protocol (MCP), providing security, observability, and management that lets organizations safely connect AI agents to their internal systems. Backed by customers including Gusto, Instacart, and Opendoor, the platform combines threat detection, detailed permissions, and enterprise development capabilities in one solution.

Taara develops free-space optical communication technology that delivers high-speed connectivity through narrow beams of light instead of fiber or radio spectrum. Spun out of X, Alphabet's Moonshot Factory, the company builds optical wireless systems and photonics technology for expanding broadband infrastructure.

Neuromorphic computing startup building brain-inspired analog hardware to achieve biology-scale energy efficiency for AI workloads, founded by former Databricks AI head Naveen Rao.

Agentic BI and data-insights platform that unifies structured/unstructured data and answers with verified source retrieval.

Arbor Energy develops supercritical CO2 turbines that deliver clean, carbon-negative power through fuel-flexible technology optimized for AI data centers and industrial applications.

Elveo Mobile (formed in 2026 by the merger of Lynk Global and Omnispace) operates a satellite direct-to-device (D2D) network that connects standard, unmodified mobile phones directly to low-Earth-orbit satellites, combining Lynk's D2D platform with Omnispace's S-band spectrum.

Foundation model company building efficient general-purpose AI systems and Liquid Foundation Models for edge and resource-constrained environments.

Semiconductor company pioneering chiplet interconnect technologies to unleash the performance of AI chips, backed by AMD, Arm, Meta, Samsung and Intel Capital

Finix is a full-stack payment processor and payments infrastructure platform that helps software platforms, marketplaces, and businesses accept payments, send payouts, manage risk, and build embedded payment experiences.

Gray Swan is a Pittsburgh-based AI security company spun out of Carnegie Mellon University, offering adversarial red-teaming (Arena, Shade) and real-time runtime protection (Cygnal) for AI models and agents. Its customers include frontier AI labs like Anthropic, OpenAI, and Meta, plus enterprises such as Snowflake.

Metriport is an open-source healthcare data infrastructure company that aggregates, cleans, and unifies patient records from EHRs, HIEs, pharmacies, and labs into a single API and data model. Its platform gives clinicians and AI agents real-time patient context at the point of care, serving customers like Amazon One Medical and Color Health.

MoonPay is a cryptocurrency payment infrastructure platform that enables users and businesses to buy, sell, and swap crypto assets through credit cards, bank transfers, and other methods.

Nace AI builds MetaModel, an AI system that dynamically generates small, task-specific language models for enterprises using a Hypernet architecture to inject task-specific weights in real-time without retraining. Their first product NAVI applies this technology to audit, compliance, and finance workflows.

Odyssey is an AI lab building interactive video and world models that generate real-time, explorable scenes for new media.

Opal Security is the authorization reasoning platform built to secure every identity, from employees and contractors to service accounts and AI agents. Provides unified visibility and defense-in-depth infrastructure for access management.

Airalo offers a global eSIM-based connectivity platform for travelers, providing affordable international mobile data packages.

Blacksmith accelerates GitHub Actions by running CI/CD workflows 2x faster at half the cost using high-performance gaming CPUs optimized for continuous integration.

Cylake is building an AI-native cybersecurity platform for enterprises requiring total data sovereignty, running entirely on-premises or in private clouds with no public cloud dependency. Founded by Palo Alto Networks founder Nir Zuk alongside Wilson Xu and Ehud Shamir (a SentinelOne co-founder), it consolidates multiple security functions into a unified, agentic system for monitoring, analysis, and incident response.

AI-powered infrastructure intelligence platform for transportation infrastructure management using LiDAR sensors, cameras, and advanced AI algorithms.

Open-access AI cloud providing fast, affordable GPU compute, serverless inference, and dedicated hosting through a decentralized marketplace, helping developers reduce AI infrastructure costs by 50-75%.

LemFi provides international payments and financial services for immigrants, offering multi-currency accounts, remittances, credit, and payments. The platform processes over $1 billion in monthly transactions across 30+ countries.

Rootly is an AI-native incident management and on-call platform that integrates with Slack to help engineering teams detect, manage, and resolve production incidents faster.

Defense technology company providing software platform for military logistics and field operations optimization.

Sequen provides real-time search, ranking, recommendation, and personalization infrastructure for consumer-internet and e-commerce companies. Its platform uses Large Event Models (LEMs) to dynamically re-rank content and products in under 50ms based on live in-session behavior (clicks, scrolls, views) rather than only historical profiles. Founded by ex-Etsy ranking lead Zoë Weil, it processes billions of monthly requests for Fortune 500 customers.

Talos provides end-to-end institutional crypto trading platform with liquidity access, automated execution, and clearing services, reaching unicorn status with $1B+ valuation.

Enterprise-grade platform running powerful AI on local devices without cloud dependency, enabling companies to work with sophisticated AI models while keeping sensitive data in place.

Anchorage Digital is an institutional crypto platform offering custody, trading, staking, and regulated banking services for digital assets.

Supply chain technology platform founded by former Amazon exec Dave Clark, integrating with inventory systems to provide AI-powered insights for revolutionizing global supply chain operations.

Catalyx Space builds orbital logistics infrastructure, combining spacecraft, software, and operations to move experiments and manufactured payloads to orbit and back. The company focuses on reusable capsules and faster, more predictable in-space deployment and downmass services.

A FinOps platform that automates cloud cost collection, allocation, and analysis to help engineering teams build cost-efficient software and improve unit economics.

Ent (incorporated as Athena Formation Inc.) builds an intent-aware workspace security platform that uses on-device AI to monitor and intervene in risky human and AI-agent actions in real time, preventing incidents before they occur. Founded by RiskIQ co-founders Elias Manousos and Brandon Dixon, it is deployed with Global 2000 customers across hospitality, financial services, and defense.

Medra develops autonomous AI-powered robotic scientists that run and refine laboratory experiments end-to-end, interfacing with standard lab tools to accelerate drug discovery and biological research.

Nous Research is an open-source AI lab developing large language models and decentralized training infrastructure, including Hermes models and the Psyche network.

SigNoz is an open-source, OpenTelemetry-native observability platform that unifies metrics, traces, and logs in a single tool, positioned as a self-hostable alternative to Datadog. It offers both self-hosted and cloud options and is used by 700+ customers with 26,000+ GitHub stars. Founded in 2020 by Pranay Prateek and Ankit Nayan, the company was part of Y Combinator and operates primarily out of India with a US entity.

Twelve Labs builds multimodal AI foundation models and an API platform for video understanding, enabling search, analysis, and reasoning over video content at scale. The company partners with AWS and NVIDIA to power 'video superintelligence' for enterprise and developer customers.

TypeSafe AI is a San Francisco AI lab building "System One Models" — machine-native models that return typed, calibrated decisions for software to consume directly, rather than generating text for humans. Its first product, Jev, serves real-time automation use cases like games, robotics, and underwriting with sub-second latency. Founded in 2024 by ex-OpenAI researcher Diogo Almeida with Erik Gafni and Sasha Sheng, it emerged from stealth in September 2026 with a $40M seed round.

Charge Robotics builds autonomous robots that construct solar farms through the Sunrise system, a portable robotic construction unit that automates the assembly and installation of solar-tracking hardware, making renewable energy deployment faster and more cost-effective.

CircleCI is a continuous integration and continuous delivery (CI/CD) platform that helps software teams automate code build, test, and deployment pipelines. Founded in 2011 and headquartered in San Francisco, it serves engineering teams across industries with cloud and on-prem offerings.

Coinflow is a payment service provider that lets merchants, web3 games, and consumer apps accept traditional card payments and settle instantly using stablecoins. Its API handles global card acceptance across 170+ countries, fraud prevention, merchant underwriting, and crypto-to-USD payouts to bank accounts. Founded in 2022 and headquartered in Chicago, it raised a $25M Series A led by Pantera Capital in October 2025.

Marketplace and tooling for transferable clean-energy tax credits, extending into broader climate finance.

Databento is a market data platform that delivers real-time and historical data on futures, options, and equities through a single API, positioning itself as a developer-first, usage-based alternative to legacy providers like Bloomberg and LSEG. Founded in 2019 by former quant trader Christina Qi, it lets trading firms, funds, and fintechs access normalized institutional-grade market data without long-term contracts.

Resend provides an email API and deliverability platform built for developers to send and manage transactional and marketing email.

Frontier AI research lab building next-generation AI models for semiconductor design. Develops recursive self-improvement cycle where AI designs silicon that powers the next generation of AI. Founded by AlphaChip creators from Google DeepMind.

Stedi is the only programmable, API-first healthcare clearinghouse, replacing legacy batch-and-portal clearinghouses with a modern cloud-native platform. It processes over 1 billion healthcare transactions per year.

Applied Compute is a San Francisco-based AI startup founded by former OpenAI researchers that builds 'Specific Intelligence' — proprietary AI agents trained on a company's own operations and data that improve with every interaction. It develops custom AI models and a forward-deployed agent platform for enterprises. The company launched publicly in October 2025 and reached a $1.3B valuation in April 2026.

Architect Labs builds AI systems that design and formally verify custom silicon, turning demanding workloads into purpose-built chips and full-stack hardware solutions. It partners with enterprises, AI labs, and governments to dramatically accelerate custom chip development timelines. Founded by Ebrahim Hussain and Aaditya Subedi (incorporated as Architect Silicon Inc.), it emerged from stealth in June 2026 with a $24M seed round led by Kindred Ventures.

David AI is the world's first dedicated audio data research lab, building the data layer for next-generation audio AI. Founded by former Scale AI engineers, serving most FAANG companies and major AI labs.

Open-source cloud infrastructure providing secure sandboxed environments for AI agents to run code and complete complex tasks, trusted by 88% of Fortune 100 companies.

Fours (formerly Suger) is an end-to-end cloud marketplace revenue engine that helps SaaS companies manage product listings, contracts, billing, and metering across AWS, Azure, and GCP.

Last Energy designs, builds, owns, and operates micro-modular nuclear power plants, most notably the PWR-20, a factory-built 20 MWe pressurized water reactor delivered as pre-fabricated modules. It sells full-service on-site baseload power to data centers, industrial facilities, and utilities, and is building a 5 MW pilot reactor at the Texas A&M-RELLIS campus. Spun out of the Energy Impact Center in 2019 by founder Bret Kugelmass, it is now headquartered in Austin, Texas.

Phantom is a leading multi-chain, self-custodial crypto wallet supporting Solana, Ethereum, Bitcoin, Base, and Polygon with over 15 million monthly active users. The platform offers token swaps, staking, NFT management, and cross-chain capabilities.

Resolve AI builds an autonomous AI Production Engineer that investigates and fixes complex production system issues end-to-end. Founded by the core creators of OpenTelemetry and former leaders of Splunk Observability, the platform automates site reliability engineering tasks.

Sent provides a unified messaging API for SMS, WhatsApp, RCS, and other channels, handling routing, compliance, templates, delivery tracking, and fallback logic for developers building communication workflows.

Stack AV develops autonomous driving technology for trucks, combining AI, robotics, and machine learning to build a self-driving ecosystem tailored to the trucking industry. The company spun out of Hyundai's self-driving unit and is based in Pittsburgh, PA.

Thread AI builds enterprise AI infrastructure with a knowledge-graph-based context engine to improve AI application accuracy and reliability.

VulcanForms is an advanced digital manufacturing company using metal additive manufacturing, precision machining, and automation to build industrial-scale production capabilities.

Energy flexibility platform-connects distributed assets with markets to decarbonize the grid.

Callosum is a London-based AI infrastructure startup founded by Cambridge University neuroscientists that builds orchestration software to route AI workloads to the cheapest suitable combination of models and chips. It raised $100 million in seed funding led by Atomico with participation from Plural, DCVC, and the UK Sovereign AI Fund, following a $10.25M pre-seed round.

Digital engineering platform focused on digital twins and secure collaboration for modeling and simulation of complex systems.

Mirendil is a San Francisco frontier AI research lab building 'AI that builds AI' — training frontier models that are expert at AI R&D and wrapping them in a product that autonomously runs research, experimentation, and optimization on its own GPUs. Founded by former Anthropic researchers, it aims to move frontier AI work outside the big labs and shorten AI R&D cycles.

Sunrise Robotics builds intelligent robotic cells for manufacturing, combining AI software, computer vision, and industrial automation to take repetitive work off factory floors.

Vesta provides mortgage infrastructure software for lenders, covering origination, processing, and servicing on a cloud platform.

Market-leading SaaS platform helping governments worldwide automate building permitting, inspection, licensing, planning, and community development with enterprise-grade cloud solutions.

Archy provides cloud software for dental practices, integrating clinical workflows, revenue cycle operations, and patient communications into one platform.

Black Forest Labs is a generative AI company that created FLUX, one of the most advanced open-source image generation models, and previously pioneered Latent Diffusion and Stable Diffusion. Founded by machine learning researchers Robin Rombach, Patrick Esser, and Andreas Blattmann, the company builds powerful creative AI models from labs in Freiburg, Germany and San Francisco. Valued at $3.25 billion after raising $300 million in Series B funding, Black Forest Labs is at the forefront of generative media technology.

SaaS platform providing state and local governments with simple permitting, licensing, and inspections solutions, reducing processing times by 75% through digital transformation.

Convex is a backend-as-a-service platform for modern web applications, combining reactive databases, server functions, and auth-ready infrastructure.

Corelight provides network detection and response (NDR) software built on the open-source Zeek framework, giving security teams deep network visibility and evidence for threat hunting and incident response. Its platform pairs network traffic analysis with AI-driven detections and integrates with SIEM, XDR, and SOC workflows. Corelight sells to large enterprises and U.S. federal and government agencies.

DatologyAI builds automated data curation tooling that selects, filters, and optimizes the training data used to build AI models. Its platform aims to cut training compute and cost while improving model quality by feeding models better data rather than more data. Founded in 2023 by ex-Meta AI/DeepMind researcher Ari Morcos with Bogdan Gaza and Matthew Leavitt, it is based in Redwood City, CA.

Lithic is a modern card issuing platform for developers, enabling businesses to create, manage, and process virtual and physical payment cards via flexible APIs.

Lumos builds an identity and SaaS management platform that helps IT and security teams automate access requests, lifecycle management, access reviews, and software spend controls from one system.

Morpho Labs builds Morpho, a decentralized, non-custodial lending protocol on Ethereum that lets users lend and borrow crypto assets without intermediaries. The protocol has grown to billions of dollars in assets supplied, with Morpho Blue offering a permissionless base layer for isolated lending markets.

Layer-1 blockchain purpose-built for stablecoins and real-world payments, born from Stripe's experience in global payments and Paradigm's expertise in crypto technology.

Terraforming robotics company that uses autonomous subsurface injection robots to lift and stabilize flood-prone terrain by injecting wood slurry deep underground, addressing urban flooding and land subsidence caused by sea level rise, extreme weather, and groundwater withdrawal with minimal surface disturbance.

Daytona provides secure, elastic sandbox infrastructure for running AI-generated code and agent workflows, giving developers and AI agents isolated, programmable environments with fast startup and persistent state.

Extropic is building thermodynamic computing hardware and software for radically more energy-efficient AI workloads. The company combines physics, chip design, and systems engineering to develop new compute architectures for next-generation intelligence.

Fin is a New York–based payments platform built for high-value, global, and instant transactions, using stablecoins to let users and businesses move millions of dollars in seconds to other Fin users, bank accounts, or crypto rails. Founded by ex-Citadel engineers Ian Krotinsky and Aashiq Dheeraj, the company was previously known as TipLink, a Solana-based link-to-send crypto wallet. It combines crypto settlement speed with traditional-finance reliability and compliance for cross-border and enterprise payments.

Flare helps security teams detect, prioritize, and remediate external cyber threats before they escalate with automated threat exposure management and security intelligence.

Flexion Robotics builds the brain for humanoid robots with an AI-driven reinforcement learning and sim-to-real autonomy platform founded by former Nvidia researchers powering humanoids across morphologies and tasks.

Forerunner builds AI-enabled software for public-sector emergency management and disaster recovery workflows, helping agencies manage grants, compliance, and program operations.

Merge provides a Unified API platform that lets B2B companies add hundreds of integrations to their products through a single integration. Covering HRIS, accounting, CRM, ATS, and file storage, Merge powers integrations for over 3,000 companies including Ramp, Drata, and AngelList.

Omen AI builds miniaturized spectroscopic sensors that continuously monitor coolant, oil, and water in AI data centers and industrial machinery, detecting contamination and equipment wear in real time. Its hardware replaces the industry's slow lab-sampling process, helping operators avoid costly cooling-loop failures in liquid-cooled AI infrastructure.

Oxide Computer Company builds rack-scale cloud computing infrastructure for enterprises that need the agility of public cloud with the control and security of on-premises hardware. Their integrated hardware-software platform delivers a complete cloud experience in a single rack unit.

PlanetScale is a managed database platform built on Vitess that helps developers ship MySQL workloads with branching, non-blocking schema changes, and global scale.

Unlimited Industries is an AI-native construction company that vertically integrates design and build for large-scale infrastructure projects including data centers, energy facilities, and advanced manufacturing. The company's proprietary AI platform can explore tens of thousands of design configurations to optimize costs and timelines, reducing pre-construction engineering from months to weeks. Founded by serial entrepreneurs and backed by Andreessen Horowitz, Unlimited is rethinking how America's critical infrastructure gets built.

Zanskar is an AI-powered geothermal exploration company that uses custom-built machine learning models to discover untapped conventional geothermal resources. The platform combines seismic characterization, directional drilling guidance, and reservoir modeling, and develops utility-scale geothermal power plants across the western United States.

Automated cloud cost optimization platform with AI-based analysis, reserved instance management, anomaly detection, and infrastructure rightsizing to help companies save up to 75% on AWS costs.

Augustus is building the Global Dollar Bank, a federally chartered clearing bank giving international fintechs and banks programmable access to US dollar and euro accounts and payment rails. Founded in 2022 by Ferdinand Dabitz and co-founders, it processes billions annually for customers like Kraken and received conditional OCC approval to charter Augustus Bank, N.A.

Chalk builds a real-time inference data platform that gives ML and AI teams low-latency feature computation, retrieval, and production orchestration for online decisioning workloads.

Networking software for AI/HPC workloads to improve reliability and throughput.

Fun builds payments infrastructure that moves money on and off blockchains, offering white-label deposit, withdrawal, orchestration, and checkout flows for fintech, DeFi/trading, and sports/gaming platforms. It is the sole deposit provider for Polymarket and also powers payment flows for Lighter and Aave, processing over $18B in annual volume. Founded in 2022 and previously in stealth, the company is headquartered in Midtown NYC and is opening a Singapore office.

Halcyon is the leading anti-ransomware and cyber resilience platform purpose-built to defeat ransomware attacks through multiple layers of prevention, detection, and recovery. Using proprietary capsule neural network AI models, it captures encryption keys and enables autonomous system recovery in minutes.

Method provides API infrastructure for consumer liability account connectivity, real-time debt data, and embedded repayment experiences across lending and fintech products.

Protege operates a governed marketplace platform for ethical sourcing of multimodal, real-world AI training data with compliant data exchange capabilities.

Raindrop is an observability and monitoring platform for AI agents, often described as 'Sentry for AI products.' The platform helps engineering teams detect, track, and fix silent failures in AI agents running in production environments. Founded by Y Combinator alumni and backed by Lightspeed Venture Partners, Raindrop provides automated issue discovery, triage, and detailed failure explanations for AI systems.

Code intelligence platform that helps developers search, understand, and fix code.

Sycamore is a Palo Alto AI infrastructure startup building a trusted agent operating system that enables enterprises to deploy, govern, and orchestrate autonomous AI agents with built-in security and human oversight. The platform supports the full agent lifecycle — discover, build, deploy, observe, and evolve — using a progressive trust framework that grants agents more autonomy as they prove reliability. Founded in fall 2025 by Sri Viswanath, former CTO of Atlassian.

Taste Labs is building the data and infrastructure layer that gives AI models and agents "taste" — the ability to judge subjective quality rather than just correctness, starting with design. It supplies frontier labs with post-training preference data, rubrics and RL/eval environments, and gives application teams context and verification tools so agent output is more on-brand and creative. The company emerged from stealth in June 2026 with an $18.5M seed co-led by CRV and Amplify Partners.

A24 is an independent entertainment company producing and distributing films, television, and related consumer media products.

Onchain governance infrastructure platform providing protocols and tools for DAOs and blockchain projects to manage voting, delegation, and community decision-making.

A biotechnology company developing carbon-negative polymers and materials using genetically engineered enzymes.

Bluecore Energy is a Long Beach-based maritime nuclear energy startup founded by Uber Freight alum Kofi Asante, building small modular water-cooled nuclear reactors mounted on floating barges to power ports, coastal infrastructure, and data centers. Its first product is a 10 MWe Pressurized Water Reactor designed to be relocated by ship and refueled only once every few years, and the company is in active review with the NRC and U.S. Coast Guard.

Botpress is an AI agent infrastructure platform that gives developers the tooling to build, deploy, and scale production-ready AI agents. Founded in 2017 and headquartered in Montréal, the company raised a $25M Series B in June 2025 to expand its agent infrastructure stack.

Finch is a unified employment API platform that enables HR tech, fintech, and benefits companies to securely read and write data across 250+ HRIS and payroll systems through a single integration. Founded via Y Combinator in 2020.

Inception (Inception Labs) is a Palo Alto-based AI research company building diffusion large language models (dLLMs) that generate text and code in parallel, delivering up to 10x faster inference and lower cost than traditional autoregressive LLMs. Its Mercury model family targets latency-sensitive, real-time applications. Founded in 2024 by Stanford professor Stefano Ermon with Aditya Grover and Volodymyr Kuleshov.

Browser infrastructure platform for AI agents with sub-150ms cold starts, built-in stealth mode, automatic CAPTCHA solving, and persistent sessions for web automations.

Identity infrastructure provider for managing access to AI agent tools with task-based permissions and dynamic policy enforcement

Mirelo builds AI for generating sound and audio layers for videos and games.

Ollama is an open model platform that lets developers download, run, and manage large language models locally on their own machines or servers via CLI, API, and cloud scaling, used to build chatbots, coding assistants, and AI agents. It is the largest developer network in the open model ecosystem, with roughly 8.9M monthly active developers and 67,000+ community-built integrations, and is used within 85% of the Fortune 500. Founded in 2023 by Jeffrey Morgan and Michael Chiang.

Phaidra builds AI agents and control systems that optimize power, cooling, and operations for data centers and other industrial facilities. Founded in 2019 by ex-Google DeepMind engineers, it partners with NVIDIA and major data center operators to improve energy efficiency.

Prefect builds workflow orchestration and AI infrastructure software that helps teams automate, observe, and manage data and application workflows.

Software supply chain security platform delivering comprehensive vulnerability management with curated near-zero-CVE open-source images, automated CVE remediation, and container hardening capabilities. Simplifies FedRAMP compliance and accelerates DevSecOps workflows.

Reka builds multimodal foundation models and enterprise AI systems that combine text, image, audio, and reasoning capabilities for production applications.

Until Labs develops reversible cryopreservation technology to pause biological time, starting with organ-scale preservation to extend the viability of donor organs for transplantation. The company is building medical infrastructure toward whole-body medical hibernation technology.

Venice is a private, uncensored AI chat and API platform founded by crypto entrepreneur Erik Voorhees and Jesse Proudman. It gives users surveillance-free access to a wide range of AI models, processing over 1.3 trillion tokens per month and 1.7 million daily API calls.

Viam is a software platform that makes the physical world programmable, enabling engineers to build, deploy, and manage robotics and IoT applications. Founded by MongoDB co-founder Eliot Horowitz, Viam powers AI and automation solutions across robotics, food and beverage, climate tech, marine, and industrial manufacturing.

You.com builds AI search and retrieval infrastructure for teams that need domain-specific, production-ready search inside their own products and workflows.

AI research company building adaptive models that learn continuously without expensive retraining, using less computing power than leading AI models, founded by former Cohere VP of Research Sara Hooker

Apex.AI builds safety-certified, developer-friendly software for autonomous and software-defined vehicles, including its Apex.Grace (formerly Apex.OS) middleware derived from the open-source ROS 2 framework. Its products power autonomous mobility and robotic systems for automotive, trucking, and agricultural-machinery OEMs. The company is headquartered in Palo Alto, California, with offices in Germany, Sweden, Japan, and South Korea.

Apollo GraphQL builds GraphOS, a cloud-native platform for building, managing, and scaling unified GraphQL APIs that orchestrate data across backend services. Its open-source tools and commercial supergraph platform are used by enterprises like Walmart, Netflix, and PayPal to accelerate application development.

Aptos Labs is the core development studio behind the Aptos blockchain, a Layer 1 proof-of-stake network built by former Meta Diem engineers using the Move programming language. The company focuses on scalable, secure decentralized infrastructure and developer tooling like the Petra wallet.

Log monitoring and observability platform for developers providing comprehensive monitoring solutions with profitability achieved in 2023

Browserbase provides cloud-hosted browser infrastructure purpose-built for AI agents and web automation. The platform enables developers to host, manage, and monitor headless browsers at scale with features including proxies, stealth mode, session recording, and debugging tools, serving over 20,000 developers.

Cortex is an internal developer portal and Engineering Operations platform that helps organizations reduce developer tax and improve operational maturity. It provides engineering teams with a centralized catalog of services, scorecards for reliability standards, and automation to foster ownership.

Elorian is a Palo Alto AI research and product lab founded in 2025 by former Google DeepMind and Apple researchers, including CEO Andrew Dai, building multimodal models for visual reasoning about images, video, spatial relationships, and the physical world. Its first model, Glimpse, launched as a research preview in October 2026, targeting applications in robotics, science, and design.

Grid-aware orchestration software that schedules AI data-center compute based on real-time power signals.

Workload as a Service platform delivering intelligent orchestration for AI workloads, eliminating inefficiencies by dynamically placing workloads on optimal compute

Geordie AI builds an AI governance platform to help enterprises adopt agentic AI safely with observability, compliance controls, and risk intelligence.

An all-in-one open source platform to securely manage application configuration and secrets like API keys and database credentials across teams and infrastructure.

Data platform for creating and managing training data for machine learning applications.

LayerZero is an omnichain interoperability protocol that enables seamless cross-chain messaging and asset transfers across 50+ blockchains. It allows developers to build decentralized applications that operate natively across multiple networks.

Legion Intelligence (formerly Yurts) builds governed AI agent-orchestration software for defense, public sector, and enterprise operations. Its platform lets organizations securely deploy, manage, and scale autonomous AI agents across sensitive networks (including IL-4/5/6) for decision support and operational intelligence, with deployments at U.S. Special Operations Command and other DoD environments.

Global payments infrastructure company building on Bitcoin and the Lightning Network, enabling instant low-cost money movement worldwide through APIs and SDKs for fiat, stablecoin, and bitcoin transfers.

Runware provides a unified AI API platform that aggregates 300+ model classes and hundreds of thousands of AI model variants behind a single consistent schema, delivering up to 10x better price and performance for generative AI applications.

SafeBreach provides a breach and attack simulation (BAS) and continuous threat exposure management (CTEM) platform that helps enterprises continuously test and validate their security controls. Founded in 2014 by Guy Bejerano and Itzik Kotler, the company is based in Sunnyvale, CA with an R&D center in Tel Aviv.

SF Compute provides rentable, large, low-cost GPU clusters for AI pre-training workloads. The platform operates as a marketplace connecting AI teams with on-demand high-performance computing capacity, offering flexible access to supercomputing-scale infrastructure with InfiniBand interconnects.

Develops advanced AI, robotic, and autonomous drone systems specifically designed for wildfire suppression, using AI to locate and knock down fires before they spread.

Substrate is America's next-generation semiconductor foundry, developing advanced X-ray lithography technology to challenge industry giants like ASML and TSMC. Founded by brothers James and Oliver Proud, the company uses compact particle accelerators to enable more cost-effective and rapid chip manufacturing in the United States. Backed by Founders Fund, General Catalyst, and In-Q-Tel, Substrate aims to restore American leadership in semiconductor production.

Urban SDK delivers geospatial AI and mobility analytics software for cities, transportation agencies, and public safety teams to improve planning and operational decisions.

Yuzu Health is a next-generation third-party administrator (TPA) that gives organizations the infrastructure to design, launch, and operate their own health insurance plans without legacy vendors. Its platform covers benefits configuration, partner integrations (PBM, stop-loss), document generation, an in-house claims adjudication engine, payments, and white-labeled member/employer/provider portals. The company supports customers in all 50 states and has facilitated over $1B in claims payments.

American Terawatt is building a national-scale high-voltage direct current (HVDC) transmission network with standardized, modular terminals to deliver hundreds of megawatts to large industrial loads, including AI data centers. The company, based in New York City and San Francisco, aims to build a 525kV, multi-terminal DC system with 14 gigawatts of capacity by 2030.

AMI Labs is a frontier AI research lab building world-model-based intelligence systems with planning, memory, and safety controls for real-world applications.

AtoB builds a financial services platform for fleets, freight brokers, factors, and logistics operators, offering fuel and spend cards, instant payments, working-capital products, fraud controls, and fleet payments infrastructure.

Basis Research Institute is a nonprofit applied AI research organization building a universal reasoning engine by establishing the mathematical principles of intelligence. The organization focuses on probabilistic programming, causal reasoning, and program synthesis to solve intractable scientific and societal problems at unprecedented scale.

Bluesky is a decentralized social network built on the AT Protocol, giving users control over their social graph and enabling an open, interoperable layer for social applications. Founded as a Public Benefit Corporation in 2021, it has grown to tens of millions of users as an open-protocol alternative to X, letting users choose their own algorithms, moderation tools, and data portability.

Chroma builds open-source data infrastructure for AI, giving developers an embeddings database and retrieval layer to add memory, search, and state to LLM applications.

CrewAI builds a multi-agent platform and open-source framework for orchestrating collaborative AI agent workflows in production applications.

Ditto builds an edge synchronization platform and mobile database that keeps apps in sync even when devices are offline or intermittently connected.

Crypto exchange infrastructure company behind Phoenix, a decentralized exchange on Solana.

GridCARE builds AI-powered grid capacity management software that identifies and activates underutilized electrical grid capacity, dramatically cutting the time needed to connect AI data centers and other large loads to the power grid. Spun out of Stanford's Doerr School of Sustainability, the Redwood City startup partners with utilities like Portland General Electric to accelerate interconnection timelines from years to months.

Inherent is a London-based frontier AI lab building Faraday, an AI system for open-ended scientific discovery where humans and self-improving AI collaborate to tackle hard problems in science. Founded by ex-DeepMind researchers, it aims to build AI that recursively self-improves to explore 'unknown unknowns' and surface paradigm-shifting research questions.

LM Studio is a desktop application and developer toolkit built by Element Labs Inc. that lets users discover, download, and run large language models locally and privately on their own hardware. It provides an OpenAI-compatible local API server and supports Windows, macOS, and Linux. Founded in 2022 by Yagil Burowski and headquartered in Brooklyn, New York.

An AI video security system that transforms existing IP cameras into intelligent agents for real-time detection and automated monitoring in healthcare and other sectors.

Mysten Labs is the core development company behind Sui, a high-performance Layer-1 blockchain built around an object-centric data model and the Move programming language. Founded by former Meta Diem/Novi engineers, it also builds Walrus decentralized storage, Seal encryption, and DeepBook on-chain trading infrastructure.

OP Labs is the core development team behind Optimism and the open-source OP Stack, a modular framework that lets enterprises, exchanges, and DeFi protocols launch their own Ethereum-compatible Layer 2 blockchains. Partners building on the OP Stack's Superchain include Coinbase's Base, Sony, Kraken, and Uniswap, with over 65% of Ethereum Layer 2 activity running through the stack.

Dynamic SaaS security platform that discovers and protects all SaaS applications, AI agents, and shadow AI tools through identity governance, configuration security, and hidden threat detection, analyzing over 100 billion interactions across 220+ SaaS app integrations.

Relace is a provider of auxiliary coding models for faster, more reliable AI code generation that makes it easy to deploy production-ready coding agents with models co-optimized with infrastructure to achieve state-of-the-art performance across million-line repositories.

StackBlitz is the creator of Bolt, an AI-powered full-stack web development platform that enables users to build, run, and deploy applications entirely in the browser. Leveraging WebContainers technology that runs Node.js natively in the browser.

StackOne provides a unified API platform for product teams to ship customer-facing integrations quickly across SaaS systems.

Token Security builds machine-first identity security to discover, govern, and secure non-human identities across cloud and SaaS environments.

Trajectory is a San Francisco research and product lab building a platform for continual learning, letting AI products keep post-training on real production signals (user edits, corrections, retries, rejections) instead of freezing after deployment. Its SDK and dashboards instrument live AI behavior, steer model optimization, and ship improvements continuously. Customers include Clay, Harvey, Decagon, Mercor, Mistral, and Rogo.

V7 provides a data engine for computer vision teams to manage datasets, label data, and train AI models at scale.

Valthos is an applied biological intelligence company developing AI and software to detect biological threats and design medical countermeasures in real time.

Allium is an enterprise-grade blockchain data platform that provides accurate, fast, and simple blockchain data across 100+ blockchains and 1000s of schemas, delivering historical and real-time data through interactive dashboards, APIs, and custom integrations for institutions and crypto enterprises.

Arcade AI is an MCP runtime platform that enables AI agents to take secure, authenticated actions across business systems. The platform provides agent-optimized tool calling, OAuth-based authorization, and governance infrastructure for production AI deployments.

Fully managed change data capture (CDC) streaming platform that replicates production databases into data warehouses and lakes in real time. Trusted by Substack, ClickUp, and Alloy, processing over 700 billion rows annually.

Codex is building a stablecoin-native blockchain designed specifically for cross-border payments and FX, providing on-ramps, off-ramps, and fiat-to-fiat transfers with built-in compliance and identity systems. The platform operates on an Ethereum Layer 2 using Optimism's tech stack, targeting payment service providers and enterprises in emerging markets.

Builds an AI-powered knowledge engine that helps security operations teams investigate alerts and automate cybersecurity workflows.

Cube is the AI-powered financial intelligence platform built for FP&A teams, providing a spreadsheet-native solution that integrates with Excel and Google Sheets to streamline financial planning, analysis, and reporting workflows.

Electronic warfare company building AI-driven software and hardware—incl. SIGINT payloads and autonomous drones—for spectrum dominance.

Enode provides an API that connects energy devices like EV chargers, batteries, and solar systems for energy apps.

Gradium is a Paris-based AI company building ultra-low latency voice foundation models that enable near-instant, expressive, and multilingual voice AI at scale. Spun out of French AI lab Kyutai, the company was founded by former Google DeepMind researchers who pioneered key advances in audio language modeling. Backed by a $70 million seed round from FirstMark Capital, Eurazeo, Eric Schmidt, and Xavier Niel, Gradium aims to make voice the universal interface for AI.

Griffin is an API-first UK bank providing a full-stack banking-as-a-service platform for companies that need regulated accounts and payments.

Isometric is an AI-native certification and registry platform for carbon removal and broader industrial climate attributes, focused on rigorous measurement, verification, and issuance.

Frontier AI lab building reasoning models that let anyone describe a game or simulation in natural language and see it transformed into a working interactive 2D/3D scene within minutes.

Parafin builds embedded finance infrastructure that lets platforms offer capital and financial services to small businesses.

Pinecone is a fully managed vector database that makes it easy to add vector search to production applications, powering AI applications with fast and scalable similarity search at any scale.

AI-driven security operations center (SOC) platform that automates alert triage, investigation, and response using agentic AI SOC analysts. Reduces investigation time by 360,000 hours and delivers 10x faster response times while reducing false positives by 96%.

Rainforest provides embedded payments infrastructure for vertical SaaS platforms, including merchant onboarding, payment operations, and payfac-as-a-service capabilities.

Speakeasy is a complete API development platform that polishes OpenAPI, generates production-ready SDKs and Terraform providers, and builds MCP servers from OpenAPI documents with extensive customization options to connect LLMs to data wherever it lives.

Turnkey provides secure, scalable, and programmable crypto wallet infrastructure for embedded wallets and onchain transaction automation. Built by the team that scaled Coinbase Custody past $100B in assets, it powers 50M+ embedded wallets.

Vantage provides cloud cost observability and optimization software for engineering and finance teams managing multi-cloud spend.

ALICE Technologies provides AI-driven construction planning and scheduling software that simulates project scenarios to improve cost and timeline outcomes.

Bespoke Labs is an applied AI company that builds the reinforcement learning environments, data curation systems, and infrastructure used to train, evaluate, and post-train reliable long-horizon AI agents for frontier labs and enterprises. It is known for open-source tooling like Bespoke Curator and open datasets. Founded in 2024 by Mahesh Sathiamoorthy and Alex Dimakis, it is headquartered in Mountain View, California.

Catena Labs builds AI-native financial infrastructure spanning agent identity, stablecoins, and banking rails so AI agents can participate in the economy safely.

Credal provides a secure AI agent platform for enterprises, enabling teams to build AI agents and MCP-connected workflows across internal data sources with governance controls.

Builds encryption infrastructure for developers, including tokenization and PCI compliance tools for payments and sensitive data.

Open-source financial infrastructure platform that provides programmable ledgers, payment connectivity, orchestration tools, and reconciliation services for building modern financial applications, trusted by companies like Booksy, Doctolib, Liberis, and Shares.

GenPeach AI develops multimodal generative foundation models for human-centric image and video creation, powering digital humans, virtual influencers, and AI companions for creative industries. Founded in 2025 and based in Zurich, Switzerland (with team members in Warsaw), it is an early-stage startup backed by angels and founders from OpenAI, Meta AI, Google DeepMind, and Microsoft AI. Per PitchBook/Nordic9 it has raised roughly $1.5M in pre-seed funding.

Langbase is a serverless AI developer platform for building, deploying, and scaling AI agents. It processes 700TB+ of vector memory and billions of AI agent runs monthly, serving 100,000+ developers with support for 600+ LLMs.

Magic is an AI coding agent company building autonomous software engineers capable of handling complex, long-horizon coding tasks. Its system combines frontier LLMs with proprietary long-context retrieval and tool-use to write, test, and deploy production-ready code.

Polymath builds simulation environments for training and evaluating long-horizon AI agents, including virtual worlds with real tools and multi-step tasks. Their flagship benchmark, Horizon-SWE, measures AI performance on end-to-end software engineering tasks, and they sell RL training infrastructure to frontier labs.

Open-source, identity-aware access proxy providing zero-trust secure access to internal applications without requiring a VPN, continuously verifying user identity and device context.

Proof provides identity-centric trust infrastructure for high-stakes digital transactions, combining identity verification, notarization, and authorization workflows.

Universal API for real-time meeting data, providing developers with recordings, transcripts, and metadata from Zoom, Google Meet, Microsoft Teams, and other video conferencing platforms. Powers over 300 enterprise clients including Instacart and Sybill.

Resilience (National Resilience, Inc.) is a contract development and manufacturing organization (CDMO) providing end-to-end biomanufacturing for biologics, vaccines, cell and gene therapies. Founded in 2020 and headquartered in Blue Ash, Ohio, it operates multiple facilities across North America and has raised over $2.5B in equity financing.

Rime builds enterprise-grade, real-time speech-to-speech AI models for handling customer phone calls, recording its own proprietary conversational voice data rather than relying on scraped audio. The company processes over 100 million calls per month for enterprise customers.

Shade is an AI-native unified file system for creative and post-production teams, combining cloud storage, real-time large-file streaming into editing tools, and natural-language search across footage and imagery. The platform consolidates the fragmented post-production stack (cloud storage, streamable file systems, media asset management, and review tools) into one system and has ingested 60M+ assets for brands, agencies, and sports organizations.

Spiral is a data infrastructure company that provides a multimodal data platform for AI, unifying governance and exposing a single API for every data modality including video, audio, geospatial, and text, engineered for machine-scale throughput to keep GPUs fully saturated.

Tracebit builds cloud-native deception technology, automatically generating and maintaining decoy resources ("canaries") across AWS, Azure, GCP, Kubernetes, CI/CD pipelines, developer workstations and identity providers. When an attacker touches a canary, it fires a high-fidelity alert, cutting breach detection from months to minutes. Founded in 2023 by ex-Tessian engineers Andy Smith (CEO) and Sam Cox (CTO), it is headquartered in London with a New York office and counts Riot Games, Snyk, Docker and Synthesia as customers.

0x (0x Labs) builds decentralized exchange infrastructure and trading APIs for DeFi, powering swap and liquidity aggregation for wallets, apps, and its own consumer product Matcha. Founded in 2017 by Will Warren and Amir Bandeali, it is backed by Greylock Partners and Jump Crypto.

Airloom Energy is reinventing wind power with a novel, low-profile track-based turbine system that dramatically reduces the cost and complexity of harnessing wind energy. Backed by Bill Gates' Breakthrough Energy Ventures and Lowercarbon Capital, the Laramie, Wyoming-based startup is developing a pilot facility to demonstrate its modular wind technology. Airloom's design uses lightweight airfoils on an oval track, offering a simpler and more affordable alternative to traditional wind turbines.

Focuses on developing AI acceleration chips and data center infrastructure tailored for running next-generation AI models.

A web3 gaming infrastructure platform providing wallet-as-a-service and payment rails for games.

Browser Use is an open-source framework that enables AI agents to autonomously navigate and interact with websites like a human user. Built by ETH Zurich alumni, the project has amassed over 80,000 GitHub stars and powers agentic AI platforms.

Checkly offers application monitoring powered by Playwright and OpenTelemetry so teams can test and monitor apps, APIs, and services as code.

Building the world's most biomimetic musculoskeletal androids featuring over 200 degrees of freedom and proprietary artificial muscles. The Protoclone V1 can be manufactured for under $20,000.

Framework designs high-performance, modular laptops that are easy to upgrade, customize, and repair, creating consumer electronics products designed to last and reduce electronic waste.

Heirloom is a direct air capture company that accelerates limestone's natural ability to absorb carbon dioxide from the atmosphere, reducing the process from years to just days. The company has built facilities in California and Louisiana to permanently remove CO2 at scale, supporting the global effort to combat climate change. Backed by Breakthrough Energy Ventures and Lowercarbon Capital, Heirloom is one of the leading carbon removal technology providers.

Ineffable Intelligence is a London-based AI research lab founded in late 2025 by David Silver, former reinforcement learning lead at Google DeepMind and creator of AlphaZero. The company is building a 'superlearner' system that discovers knowledge purely through self-directed experience and reinforcement learning, without relying on human-generated data. Its stated mission is to make first contact with superintelligence.

Inference provides a distributed, serverless platform that lets developers run open-source AI models without managing infrastructure. The company aggregates underutilized data center capacity to offer cost-effective LLM inference via a simple API.

Self-healing software platform that automates bug detection, diagnosis, and resolution, enabling applications to fix user experience issues before humans intervene. Backed by Y Combinator (S25), Vercel, and Designer Fund.

Mechanical Orchard uses AI to modernize legacy enterprise software and mainframe systems, helping large organizations transform older codebases while preserving critical business logic. Its product, Imogen, captures actual system behavior to guide incremental rewrites into modern cloud-native code. Founded by Rob Mee (ex-CEO of Pivotal Labs), it targets enterprises seeking to reduce technical debt without disrupting operations.

Micruity provides retirement-income data infrastructure connecting recordkeepers, insurers, and asset managers to operationalize lifetime income products.

MotherDuck is a serverless cloud data warehouse built on the open-source DuckDB engine, enabling fast SQL analytics with no infrastructure to manage. The platform supports hybrid local-cloud execution, allowing analysts to query data seamlessly across laptop and cloud.

A Layer 1 blockchain designed from the ground up for the AI era, building a planetary-scale verifiable supercomputer that concentrates the world's compute into a single blockchain.

Unified ingress platform providing developers with secure tunnels, reverse proxy, API gateway, and global load balancing used by over 7 million developers worldwide.

Nile is a Postgres backend for modern B2B SaaS applications, bundling multi-tenant primitives like auth, authorization, and tenant-aware data infrastructure.

Playbook is a creative file manager designed specifically for designers, serving as a beautifully organized cloud storage and sharing platform. The platform uses image tagging technology to transform files into expressive Pinterest-style galleries, making it easy for designers to store, organize, and share their creative work.

Pulumi builds an infrastructure as code platform that lets engineers define and manage cloud infrastructure using general-purpose programming languages such as TypeScript, Python, Go, C#, and Java instead of bespoke DSLs. Its open-source engine is paired with Pulumi Cloud, a managed service for state, secrets, policy, and team collaboration across AWS, Azure, Google Cloud, and Kubernetes. The company is remote-first, headquartered in Seattle, and hires through Greenhouse.

Quilter uses physics-driven AI to fully automate PCB layout design, converting schematics into fabrication-ready boards in hours rather than weeks. Integrates with Altium, Cadence, and Siemens.

Railway offers a cloud deployment platform that helps engineering teams ship and operate applications and databases with minimal infrastructure overhead.

Decentralized blockchain AI platform enabling collaborative AI development with secure asset control.

dottxt builds structured generation tooling for production LLM applications, helping developers force reliable outputs that plug into existing software systems.

Activeloop provides a data platform for AI and unstructured data, helping teams build, manage, and query multimodal datasets for AI search and model training.

Alpen Labs builds Bitcoin infrastructure and cryptography tooling, using zero-knowledge proofs to deliver a modular rollup that makes Bitcoin scalable, private, and programmable. The remote-first team of cryptographers and engineers (ex-Blockstream, Palantir, Nethermind) is building financial rails on Bitcoin, including lending and BTC yield products. Founded in 2022, it has raised $19.1M across a seed round led by Ribbit Capital and a January 2025 strategic round led by DBA and Cyber Fund.

Arcol is a cloud-native, browser-based BIM platform for architects, often described as Figma for BIM. It enables real-time 3D collaborative building design with construction intelligence at its core.

bem provides a production layer for unstructured data, turning documents, audio, images, and other messy inputs into deterministic, schema-enforced outputs for operational workflows.

Cake provides enterprise AI infrastructure for highly regulated industries, helping teams deploy compliant, governed AI workloads with managed open-source components.

Clerk provides developer-first authentication and user management infrastructure, including embeddable sign-in flows, session management, organizations, and backend APIs for modern web applications.

A company building quantum computers on silicon chips using AI software to create qubits 1000x faster than current manual methods.

David Energy builds clean energy software and operates as a technology-driven retail electricity supplier, optimizing how commercial and industrial customers consume, manage, and distribute power. Its platform integrates distributed energy resources like batteries and solar to run buildings on clean energy around the clock while lowering costs. The New York-based company competes directly with legacy utility incumbents.

Flox builds reproducible development environments for enterprise software teams, built on Nix with Nix knowledge optional. Its platform delivers cryptographically pinned environments that stay identical from a developer's laptop through CI to production, eliminating environment drift and strengthening software supply chain security. A spinout of the D. E. Shaw group, Flox offers both an open-source platform and enterprise SaaS.

Graphon AI is a pre-model intelligence layer that transforms enterprise multimodal data (documents, video, audio, logs, databases) into persistent relational memory using graphon mathematical functions. It enables LLMs and AI agents to reason accurately across unlimited connected data sources with larger effective context. The company was founded by researchers from Amazon, Meta, MIT, Google, Apple, and NVIDIA.

Griting is an AI-native talent infrastructure company that makes capability provable through evidence-based, traceable evaluation—an evidence-first system designed for trustworthy talent decisions.

HoneyHive provides observability, evaluation, and monitoring tools for teams building production AI agents.

Imbue (formerly Generally Intelligent) is an AI research lab building agents that can robustly reason and code. The team trains foundation models optimized for reasoning and ships applied tools (Sculptor, Bouncer) that let anyone build and control custom AI agents. The company has raised over $200M to support its long-term mission.

Impilo provides full-stack digital health infrastructure for remote patient monitoring, combining device logistics (4PL), an e-commerce/API layer, and patient support so healthcare organizations can deploy and manage at-home monitoring devices. Its middleware connects providers, devices, and data to enable remote care and diagnostics. The Philadelphia-based company serves hospitals and digital health companies running RPM programs.

Lookout is a San Francisco-founded (now Boston-headquartered) cybersecurity company providing mobile endpoint security and threat intelligence for enterprises, protecting smartphones and tablets from phishing, malware, and network-based attacks. It serves 2,000+ enterprise customers and telecom carrier partners, having divested its consumer app and cloud SSE business to focus on mobile-first endpoint protection.

Embedded analytics platform enabling SaaS companies to build and deploy customer-facing dashboards directly into their products with drag-and-drop interfaces and code-based SDKs.

New Lantern builds an AI-powered cloud-native PACS platform that automates radiology workflows. Its AI Radiology Resident suite handles imaging and reporting tasks, enabling radiologists to work faster and more accurately across all modalities.

Open-source, ACID-compliant search & analytics database—an Elasticsearch alternative built on PostgreSQL.

Plural provides a Kubernetes management platform for deploying, operating, and governing fleets across cloud environments.

Provides AI-powered mapping tools like Farsight to help defense teams generate 3D terrain and plan missions.

Decentralized open-source AGI platform backed by Founders Fund and Pantera Capital, building an open AGI network where multiple AI agents collaborate in real time to prevent single-entity AGI control.

Sentra provides cloud-native Data Security Posture Management platform, securing enterprise data for AI adoption with 300% YoY revenue growth and multiple Fortune 500 customers.

AI-led B2B payments platform offering order-to-cash workflow automation including checkout, risk assessment, payment reconciliation, and cash management, deployed on platforms like Walmart, Alibaba, IKEA, and Samsung.

Sweet Security provides runtime-powered CNAPP and AI security software that helps enterprises discover assets, detect attacks, reduce vulnerability noise, and investigate incidents faster.

Universal staking protocol offering a modular coordination framework for blockchain ecosystem, enabling protocols to evolve security models and unlock new economic primitives with over $2.7B peak TVL.

An agentic data security platform that autonomously scans, catalogs, and classifies data in motion and at rest while automating remediations for the AI era.

Semantic KV caching layer built for LLM inference, enabling AI applications to reduce inference costs and latency by reusing cached computation across similar prompts.

Generates realistic synthetic data to power software testing and analytics without exposing sensitive production data.

Unit provides embeddable banking and lending products that enable software platforms to integrate financial services—including accounts, money movement, card issuing, and capital products—directly into their products. Processes over $80B in annual transactions.

Voliro develops autonomous aerial robotics for industrial inspections, combining a drone platform, tiltable payload system, and software for high-value asset inspection workflows.

Physical AI company building Newton foundation model that fuses real-time multimodal sensor data with natural language to interpret and act on physical phenomena

Axiom is a cloud-native observability platform providing serverless log management, tracing, and AI telemetry. It eliminates the need to manage complex infrastructure or worry about data limits when storing and querying event data.

Building a privacy-preserving Ethereum Layer 2 with programmable privacy and client-side proofs.

Butlr is a privacy-first ambient sensing platform spun out of MIT Media Lab that uses thermal sensors and AI to detect human presence, occupancy, and posture without capturing personally identifiable information. The sensors serve enterprises across workplace optimization, senior living, and building energy management.

CapitalOS provides embedded spend management infrastructure for vertical SaaS platforms, enabling business credit and spend controls via API integrations for platform customers.

Cellares is an integrated development and manufacturing organization (IDMO) for cell therapies, using automation and industrial-scale manufacturing systems to expand access to life-saving treatments.

Ceramic.ai builds enterprise AI training infrastructure that improves the speed, efficiency, and scalability of large-model development.

Chestnut Carbon develops and manages U.S. nature-based carbon removal projects, primarily through reforestation and afforestation on farmland and degraded land. The company uses proprietary MRV (Measurement, Reporting, and Verification) technology and data modeling to identify optimal land parcels, accelerate carbon measurement, and reduce monitoring costs. Projects adhere to Gold Standard verification and span 37 states, conserving over 200,000 acres and targeting removal of over 100 million tons of carbon over project lifetimes.

Cleric builds an AI site reliability engineer that investigates incidents, reasons across production signals, and helps engineering teams resolve operational issues faster.

Cover designs and manufactures custom modular residential structures in a factory and assembles them on-site in weeks. The company uses proprietary design software and a steel-frame building system for ADUs and backyard homes.

Daylight is a decentralized energy company using software, financing, and crypto-native infrastructure to accelerate home electrification. The platform helps households adopt clean energy products while coordinating distributed energy and financing workflows.

Discovery Loop is a Palo Alto public benefit corporation founded in August 2026 by ex-Google AI leaders Jeff Dean, Sanjay Ghemawat, Oriol Vinyals, and Quoc Le. It is building autonomous AI systems to automate the scientific method — proposing, running, and evaluating experiments at scale across machine learning, science, and engineering.

Divine Research builds an undercollateralized lending system using stablecoins on World Chain. Since launching in December 2024, it has issued over 1 million loans to 900,000+ unique borrowers without requiring collateral or credit history.

Dub is an open-source link attribution platform that powers short links, QR codes, conversion tracking, and affiliate programs for modern marketing teams. Used by over 1,000 companies including Twilio, Vercel, Perplexity, and Buffer, it provides advanced analytics and branded link management infrastructure.

Fastino builds task-specific language models and small-model infrastructure for production AI workloads, focused on speed, accuracy, and agentic AI use cases.

FlutterFlow is a low-code visual development platform for building native mobile and web applications, used by over 1.3 million developers across 200+ countries.

Fly.io is a developer-focused public cloud platform that runs full-stack apps, databases, and persistent compute close to end users across a globally distributed network. Founded in 2017, it has shifted focus toward durable infrastructure for AI agents, with former Docker CEO Scott Johnston joining as CEO in 2026.

Decentralized protocol that executes and verifies machine learning workloads across any device, unifying global compute into a single open network.

Guild.ai is a San Francisco company building a control plane for AI agents in the enterprise. The platform lets teams build, deploy, govern, and share agents in production, enforcing identity and permissions at the moment of action while recording every input and tool call for audit and reversibility. It is code-first, model-agnostic, and vendor-neutral, with security and observability built into the runtime.

Bot protection and anti-fraud security platform with transparent, CAPTCHA-free defense.

Kingdom Supercultures engineers microbes to create functional ingredients for food and beverage brands.

Open-source metering and usage-based billing platform that enables SaaS companies to build flexible pricing models with consumption tracking, subscription management, and payment orchestration.

Developer observability for live apps: dynamic logs, metrics, traces without restarts.

M0 builds programmable stablecoin infrastructure for financial institutions, providing minting, settlement, treasury, and compliance primitives for digital dollar products.

Mem0 is a universal, self-improving memory layer for LLM applications that enables them to remember and learn from user interactions over time, powering personalized AI experiences with over 41,000 GitHub stars and 14 million Python package downloads.

Niteshift is a New York-based cloud platform for AI coding agents, letting teams define their dev environment, services, and automations once and run any frontier agent (Claude Code, Codex, OpenCode) against a real application stack. The platform handles runtime, databases, auth, testing, and verification workflows so agents can build and validate software autonomously, and is deliberately model- and vendor-agnostic. Founded by former early Datadog engineering leaders Sajid Mehmood and Conor Branagan.

Osium AI builds an AI platform for materials and chemicals R&D, helping industrial teams accelerate discovery, formulation, and optimization workflows.

Paragon is an embedded integration platform that enables SaaS companies to rapidly build and ship production-grade third-party integrations without building each connector from scratch.

Pipedream Labs is building an autonomous underground delivery network using robotic carts that travel through buried tubes at speeds exceeding 60 mph, making delivery feel like teleportation. The company aims to eliminate emissions, reduce traffic congestion, and dramatically lower last-mile delivery costs.

poetiq is an AI research and engineering company building reasoning systems and self-improving intelligence infrastructure, founded by former Google DeepMind researchers.

Popcorn is a next-generation telco built software-first, offering a $69/month global mobile plan covering 180+ countries with no roaming fees, eSIM activation, and AI-powered call screening.

Positron develops AI inference hardware and systems designed to deliver lower-cost, lower-power deployment for large language models and other modern AI workloads.

Provides a unified interface to design AI workflows by connecting data, models, and automations.

Radical AI is building next-generation AI infrastructure with a focus on custom silicon and compute systems optimized for large-scale model training and inference. It aims to reduce the cost and energy consumption of AI workloads through purpose-built hardware and software co-design.

Climate data company deploying high-altitude balloons to gather atmospheric measurements and improve weather forecasting models.

Sphere Labs (Sphere Laboratories, Inc.) builds SpherePay, a global stablecoin payments API and dashboard that lets businesses move dollars across borders and settle in under 30 minutes across 160+ markets. The platform handles fiat/stablecoin on- and off-ramps, cross-border settlement via local banking partners, treasury and liquidity management, and local compliance. It is also developing SphereNet, its own payments network.

Stable Sea provides global stablecoin-to-fiat offramp infrastructure for businesses, enabling programmatic conversion of stablecoins to local currencies across 40+ countries through a unified API.

Superlinked builds information retrieval infrastructure for AI applications, combining multimodal and structured signals to improve enterprise search and matching.

Syenta develops Localized Electrochemical Manufacturing (LEM) technology for advanced semiconductor chip packaging, enabling scalable, high-density interconnects without traditional lithography. Spun out from the Australian National University, their approach addresses memory bandwidth bottlenecks in AI computing.

SynthBee is an AI-native technology company building enterprise AI and cloud infrastructure solutions, with hiring currently routed through Gusto-hosted postings.

Tella makes screen recording and async video creation tools for entrepreneurs and teams, combining capture, editing, and sharing in a single product.

Thunder Compute builds GPU virtualization software that pools idle GPU capacity across data centers, letting cloud providers and enterprises schedule workloads far more efficiently. Founded in 2024 by Carl Peterson and Brian Model, the company aims to become the "VMware for GPUs" and has already served over 10,000 users on its own cloud.

Tinybird is a real-time data platform that enables data and engineering teams to build real-time data products and APIs at scale. The platform ingests, transforms, and serves large volumes of data with sub-second latency for analytics and operational intelligence.

Transcend is an enterprise-grade data privacy infrastructure platform that serves as the compliance layer for customer data. It enables organizations to automate data subject requests, map data across systems, manage consent, and activate data for AI responsibly at scale.

Company behind TruffleHog, a leading open-source secret scanning tool with 15M+ downloads that detects, verifies, and remediates leaked API keys, tokens, and credentials across code repositories.

Wafer builds autonomous AI agents that act as performance engineers, continuously profiling and optimizing AI inference workloads across models, serving engines, kernels, and hardware (including non-Nvidia chips like AMD's). The San Francisco company offers dedicated and serverless inference for open-source models and reached roughly $8M in annualized revenue within months of launch.

1001 is a GCC- and London-based deep-tech startup building a localized, sovereign AI operating system for critical physical infrastructure — aviation, ports, shipping, and energy. Its platform builds live operational models of complex systems to predict failures, automate high-stakes decisions, and optimize physical workflows. Founded by ex-Scale AI operator Bilal Abu-Ghazaleh, it embeds forward-deployed engineers with Gulf infrastructure operators.

1Money is building the world's first Layer 1 blockchain protocol designed exclusively for stablecoin payments. Founded by former Binance.US CEO Brian Shroder, the network targets enterprise-grade payment use cases with the fastest and most compliant infrastructure.

Decentralized AI search network for the Web3 Internet providing personalized search experiences and helping developers build custom search functionalities

Aether AI is a frontier AI research company building causal world models — systems that reason through causal mechanisms rather than statistical correlations, so machines can reason under interventions and act reliably in complex real-world environments. Founded by UC San Diego professor and causal-discovery researcher Biwei Huang, its initial commercial focus is Physical AI and robotics. The company raised a $20M seed round in June 2026 led by MPCi.

Airbase builds a software platform for radio-frequency spectrum licensing, coordination, and intelligence, using AI pipelines to turn fragmented analog federal spectrum records into a real-time, machine-readable data layer for interference deconfliction. The dual-use, New York-based startup launched with an active federal government contract and is pursuing further Department of Defense deals.

Aleo is a Layer-1 blockchain built around zero-knowledge cryptography, enabling private, programmable, and scalable decentralized applications and payments. Founded in 2019 by Howard Wu, Collin Chin, Raymond Chu, and Michael Beller, it is now stewarded in part by the nonprofit Aleo Network Foundation.

Anaconda provides the world's most popular open-source Python and R distribution for data science and AI development. Serving over 45 million users, its platform enables enterprises to manage packages, environments, and AI workflows at scale with security and governance controls.

Apex Intelligence is a Beijing-based foundation model research lab building self-evolving AI systems for open-ended scientific discovery, aiming to position AI as a co-researcher rather than an assistive tool. Founded in June 2026 by Tsinghua professor Yongchao Chen, its team includes researchers from Google, Microsoft, Amazon, Kimi, Zhipu AI, Ant Group, Tsinghua, Harvard, MIT, and the University of Michigan.