Manufacturing AI Startup Jobs

Tractian is a Manufacturing AI company providing industrial maintenance and reliability solutions, combining hardware, sensors, software and AI to modernize manufacturing maintenance processes as the Industrial Copilot.

A robotics company providing robotic solutions for wind turbine blade maintenance and inspection, using specialized robots for cleaning, coating, and repair.

General Matter is rebuilding domestic uranium enrichment capacity in the U.S., developing low-enriched and high-assay low-enriched uranium to support advanced nuclear power and American energy security.

Autonomous drone manufacturer building AI-powered drones for defense, public safety, and enterprise inspection.

Defense technology company building unmanned defense systems and distributed manufacturing.

Varda Space Industries is a space manufacturing company that designs, builds, and flies spacecraft to produce pharmaceuticals in microgravity and return them to Earth:contentReference[oaicite:28]{index=28}.

Robotics company using wall-climbing robots and AI for industrial inspections and predictive maintenance.

Nominal provides the connected hardware test stack used to capture telemetry, validate systems, and ship complex hardware faster. Its software supports aerospace, defense, and industrial teams running mission-critical test and operations workflows.

Defense technology company providing software platform for military logistics and field operations optimization.

AI analytics platform for building materials and home improvement manufacturers.

Aetherflux develops space-based solar power systems that collect energy in orbit and transmit it to Earth.

Develops factory-fabricated modular nuclear microreactors designed for AI data centers and industrial applications. The Aalo Pod is a 50 MWe power plant purpose-built for data centers.

Airbound builds the world's most efficient delivery drones, developing advanced autonomous aircraft using blended-wing-body designs for ultra-low-cost logistics. Founded by 20-year-old Naman Pushp, the Bengaluru-based company aims to achieve one-cent drone deliveries at scale, serving medical, defense, and industrial applications.

Airloom Energy is reinventing wind power with a novel, low-profile track-based turbine system that dramatically reduces the cost and complexity of harnessing wind energy. Backed by Bill Gates' Breakthrough Energy Ventures and Lowercarbon Capital, the Laramie, Wyoming-based startup is developing a pilot facility to demonstrate its modular wind technology. Airloom's design uses lightweight airfoils on an oval track, offering a simpler and more affordable alternative to traditional wind turbines.

ALSO. is an electric mobility company spun out of Rivian that is building small, vertically integrated EVs for dense urban movement and autonomous delivery. Its vehicles combine new propulsion, software, and hardware to replace short car trips with lighter electric transport.

Antares is developing mass-producible, inherently safe nuclear microreactors for terrestrial, underwater, and space-based applications, producing between 100 kilowatts and 1 megawatt of electricity. The company has a 145,000-square-foot manufacturing facility in Torrance, California and is on track to achieve first reactor criticality by mid-2026. Founded by alumni of SpaceX, MIT, and Los Alamos National Lab, Antares is backed by over $130 million in venture capital and government funding.

A biotechnology company developing carbon-negative polymers and materials using genetically engineered enzymes.

Apex manufactures productized satellite bus platforms for constellation-scale missions, aiming to remove the satellite production bottleneck. The company focuses on standardized spacecraft, fast lead times, and high-rate manufacturing for commercial and defense customers.

Arbor Energy develops supercritical CO2 turbines that deliver clean, carbon-negative power through fuel-flexible technology optimized for AI data centers and industrial applications.

Arcade is an AI product creation platform that connects designers with makers to bring physical products to market.

AstroForge is a deep-space mining company focused on extracting valuable metals from asteroids, particularly platinum group metals (PGMs) and critical minerals. The company develops technology to locate, reach, and mine asteroids to provide sustainable resources for Earth and space industries.

Atomic Industries is an AI-powered tool-and-die manufacturer that applies machine learning to modernize precision manufacturing.

Augrade is an AI-powered spatial computing platform that automates heavy industry design and engineering, generating manufacturing and construction-grade CAD models in minutes.

Fusion energy startup developing modular micro-fusion reactors for compact, scalable clean power and propulsion applications.

Ayar Labs builds optical I/O and in-package photonics technology to reduce data-movement bottlenecks in large-scale AI and high-performance computing systems.

Backflip AI turns text prompts into 3D models and design-ready assets for physical products.

Base Power is building America's next-gen power company by deploying whole-home battery backup systems that protect families from outages and strengthen the grid. Deployed over 100MWh of residential battery capacity.

BotBuilt develops robotics and automation systems for homebuilding, including robotic framing workflows to improve speed and labor efficiency.

Bright Machines provides software-defined manufacturing and industrial automation systems that combine robotics, AI, and computer vision for electronics production.

A cloud-based software platform designed for commercial contractors (MEP, Fire Life and Safety) to manage projects, field service, job costing, and scheduling in an all-in-one solution.

Climate tech company building a carbon-smart wood supply chain and marketplace for reclaimed timber.

A venture-backed defense tech company building mass-producible hypersonic weapons systems using modern hardware development and manufacturing processes.

Catalyx Space builds orbital logistics infrastructure, combining spacecraft, software, and operations to move experiments and manufactured payloads to orbit and back. The company focuses on reusable capsules and faster, more predictable in-space deployment and downmass services.

Cellares is an integrated development and manufacturing organization (IDMO) for cell therapies, using automation and industrial-scale manufacturing systems to expand access to life-saving treatments.

CesiumAstro builds communications systems and phased-array hardware/software for space, air, and ground missions, supporting satellite and defense connectivity use cases.

A defense technology company specializing in counter-drone radar and other defense solutions.

Charge Robotics builds autonomous robots that construct solar farms through the Sunrise system, a portable robotic construction unit that automates the assembly and installation of solar-tracking hardware, making renewable energy deployment faster and more cost-effective.

Building the world's most biomimetic musculoskeletal androids featuring over 200 degrees of freedom and proprietary artificial muscles. The Protoclone V1 can be manufactured for under $20,000.

Colossal Biosciences is a genetic engineering and de-extinction company using CRISPR technology to restore extinct species like the woolly mammoth and protect critically endangered ecosystems.

Conifer develops compact, rare-earth-free electric powertrains using patented axial flux motor technology and ferrite magnets. Founded by ex-Apple and Lucid engineers, the company's software-driven manufacturing approach enables cost-effective, supply-chain-resilient motors for two- and four-wheel vehicles, lawn equipment, and tractors.

Copper is a Berkeley-based startup that makes battery-equipped induction stoves that plug into regular 120V outlets, enabling easy upgrades from gas to induction without costly electrical work, combining premium cooking performance with grid-supporting battery technology.

Cresilon develops hemostatic medical devices, including gel-based technologies that rapidly stop bleeding for human and animal care.

Frontier AI company on a mission to solve breakthrough materials discovery using generative AI and advanced molecular simulations, compressing decades of R&D into months.

Electronic warfare company building AI-driven software and hardware—incl. SIGINT payloads and autonomous drones—for spectrum dominance.

Debut is a beauty biotechnology company that uses AI-powered ingredient discovery and biofermentation to create high-performing, sustainable beauty ingredients from molecules that nature produces only in minute quantities. Named one of TIME100 Most Innovative Companies in 2025, the company partners with major brands like L'Oreal to develop next-generation skincare actives with a focus on skin longevity. Headquartered in San Diego, Debut has raised over $89 million and screens billions of candidate molecules through its proprietary platform.

Dexterity develops physical AI robotic systems for industrial automation, enabling warehouses and logistics operations to automate complex manipulation tasks.

AI-driven manufacturing platform that automates the creation and management of model-based work instructions from CAD files. BuildOS generates 3D animations of assembly steps, reducing documentation time from weeks to hours.

Builds and operates automated drill rigs to accelerate mineral discovery, integrating autonomous control systems and real-time data streams into diamond core drilling for mineral exploration.

Dusty Robotics develops robotic layout systems for construction teams, including the FieldPrinter platform for translating BIM plans to jobsites.

Dyna Robotics develops high-performance general-purpose robots powered by proprietary embodied AI foundation models that achieve 99+ percent success rates in commercial environments with self-improving capabilities.

Efficient Computer builds the world's most energy-efficient general-purpose processor, the Electron E1, offering up to 100x greater efficiency than traditional CPUs. Spun out of Carnegie Mellon University, their Fabric architecture minimizes data movement, enabling applications in AI, edge computing, space, defense, and consumer devices.

Semiconductor company pioneering chiplet interconnect technologies to unleash the performance of AI chips, backed by AMD, Arm, Meta, Samsung and Intel Capital

Building application-specific AI chips (Sohu) optimized for transformer inference with 10x throughput gains.

Extropic is building thermodynamic computing hardware and software for radically more energy-efficient AI workloads. The company combines physics, chip design, and systems engineering to develop new compute architectures for next-generation intelligence.

Advanced manufacturing company using breakthrough Electrochemical Additive Manufacturing technology to 3D print next-generation electronics components for thermal management, wireless communications and power electronics

Figure develops general-purpose humanoid robots and embodied AI systems for industrial and logistics environments, combining robotics hardware with AI control systems.

Flexion Robotics builds the brain for humanoid robots with an AI-driven reinforcement learning and sim-to-real autonomy platform founded by former Nvidia researchers powering humanoids across morphologies and tasks.

Flow Computing develops Parallel Processing Unit technology to accelerate next-generation CPUs for AI, edge, cloud, and parallel computing workloads.

Framework designs high-performance, modular laptops that are easy to upgrade, customize, and repair, creating consumer electronics products designed to last and reduce electronic waste.

Grid Aero builds autonomous cargo aircraft for long-range, high-payload logistics solutions serving both military and commercial applications with rapid development cycles.

Deep-tech mining and energy startup developing proprietary laser-based drilling systems to unlock Europe's critical minerals and geothermal energy at extreme depths. Building Europe's first technology-driven mining and energy platform with plans to begin selling European-mined critical raw materials by 2029.

Hadrian is a manufacturing startup using AI and robotics to automate the production of defense and aerospace components:contentReference[oaicite:14]{index=14}.

Hanomi builds AI software for mechanical engineering teams, turning 3D CAD models into production-ready drawings and structured manufacturing knowledge.

Heirloom is a direct air capture company that accelerates limestone's natural ability to absorb carbon dioxide from the atmosphere, reducing the process from years to just days. The company has built facilities in California and Louisiana to permanently remove CO2 at scale, supporting the global effort to combat climate change. Backed by Breakthrough Energy Ventures and Lowercarbon Capital, Heirloom is one of the leading carbon removal technology providers.

AI-powered manufacturing platform that ships custom factory software rapidly with agents that write code and deliver a live Factory OS in 24 hours.

Home electrification company accelerating decarbonization with next-generation battery-integrated induction appliances for sustainable homes

Inversion Space is turning space into a transportation layer for Earth by building autonomous re-entry vehicles that enable precision delivery of cargo to anywhere on the planet in under an hour, creating an on-demand logistics network in Low-Earth Orbit.

Vertically integrated home electrification company deploying affordable all-electric heat pump systems across North America, reducing upgrade costs up to 50% with over 1,000 installations to date

London-based direct-to-consumer fresh cat food platform delivering personalized nutrition, having served over 100 million fresh meals and captured 2% of the UK cat food market

Keychain is an AI-powered platform for CPG manufacturing that connects brands and retailers with a global network of over 30,000 vetted manufacturers. Its KeychainOS operating system helps manufacturers manage production cycles with AI-driven compliance, planning, and traceability modules.

Kingdom Supercultures engineers microbes to create functional ingredients for food and beverage brands.

LeydenJar develops and produces pure silicon anodes for energy-dense batteries, enabling 70% more energy storage while reducing CO2 emissions by 85% with 7-minute charging capability.

Lightship is the first American all-electric recreational vehicle company, designing and producing aerodynamic, battery-powered travel trailers. Founded by Tesla alumni, the company builds zero-emission travel trailers including the Atmos and Panos models, with deliveries starting in 2026. Lightship is headquartered in Broomfield, Colorado.

Liquid Death is a better-for-you beverage brand selling canned water, iced tea, and sparkling energy with a sustainability-focused, entertainment-driven consumer brand.

Premium bottled water brand offering purified spring water from protected mountain springs in Southern California, exclusively in glass bottles. Features chemical-free membrane filtration, precise mineralization with trace magnesium and Celtic sea salt, third-party lab verification accessible via QR codes, PFAS-free, plastic-free, and NSF certified for transparency and purity.

Machina Labs develops AI-powered robotic manufacturing systems for sheet metal forming and industrial production, reducing the need for traditional tooling.

MaintainX provides a cloud-based maintenance and operations platform that automates tasks like work orders, inspections, and safety procedures:contentReference[oaicite:15]{index=15}.

Medra develops autonomous AI-powered robotic scientists that run and refine laboratory experiments end-to-end, interfacing with standard lab tools to accelerate drug discovery and biological research.

Construction management software providing contractors with time tracking, payroll, compliance, and payment solutions for construction workflows

Monumental develops AI-powered autonomous robots for on-site masonry construction work, performing bricklaying with millimeter precision using computer vision to make construction software-defined and autonomous.

Morpheus Space develops electric propulsion systems and mobility solutions for satellites, including modular thrusters for commercial and government space missions.

Regenerative medicine company developing stem cell-derived tissue and organ replacement therapies for liver disease using iPSC-derived platform technology, with operations in Montreal, Cambridge and Toronto

Mythic builds power-efficient analog compute technology for AI inference, targeting edge-to-enterprise deployments where energy efficiency and throughput are critical.

Nexxa builds specialized AI agents that automate complex technical workflows in heavy industries using multi-agent architecture and computer use capabilities.

Normal builds AI systems and thermodynamic computing hardware to accelerate semiconductor design and improve energy efficiency in compute. The company works with large chip and manufacturing partners while developing its own next-generation computing architecture.

Builds autonomous systems and AI-native infrastructure for U.S. industrial supply chains focused on defense manufacturing.

Northwood Space designs and manufactures electronically steered phased-array ground stations that enable scalable, rapidly deployable satellite communication and tracking infrastructure. The company serves commercial and government customers including a $50M U.S. Space Force contract to modernize the Satellite Control Network.

NovoLINC develops breakthrough nanostructured thermal interface materials for AI computing, data centers, and high-power electronics. Its proprietary technology achieves 10X lower thermal resistance than conventional materials, enabling better heat dissipation for next-generation semiconductor chips and cooling critical AI infrastructure.

Building vertically integrated, automated metal factories in Detroit that deliver raw materials faster, cheaper, and more reliably to US manufacturers. Software-driven quoting in milliseconds.

Olipop is a prebiotic soda brand creating healthier alternatives to traditional sodas, using plant fiber and botanicals to support digestive health while delivering classic soda flavors.

Orchard builds AI-powered robotic systems that automate orchard harvesting with computer vision and advanced robotics.

Osium AI builds an AI platform for materials and chemicals R&D, helping industrial teams accelerate discovery, formulation, and optimization workflows.

Osmo uses AI-powered olfactory intelligence to digitize and generate custom scent formulas, building the world's first AI-powered fragrance house with robotic production capabilities.

Oxide Computer Company builds rack-scale cloud computing infrastructure for enterprises that need the agility of public cloud with the control and security of on-premises hardware. Their integrated hardware-software platform delivers a complete cloud experience in a single rack unit.

Engineering general intelligence (“Archie”) that performs quantitative and spatial reasoning for physical engineering.

Pacific Fusion is building a high-gain pulsed magnetic fusion system designed to achieve net facility gain, delivering more fusion energy output than all stored energy input. The company develops affordable, modular fusion technology using common materials to provide abundant, clean energy for a prosperous planet.

Robotics AI company building foundation models for general-purpose robots to handle physical world interactions with advanced manipulation capabilities

PhysicsX is an AI company accelerating industrial innovation by combining AI-driven multiphysics inference with numerical simulation to improve the design, manufacturing, and operation of complex products. Founded in 2019 by former Formula 1 engineers, the platform serves enterprises across aerospace, defense, automotive, semiconductors, and energy sectors. PhysicsX raised over $155M including investments from NVIDIA, Atomico, and Temasek.

Pipedream Labs is building an autonomous underground delivery network using robotic carts that travel through buried tubes at speeds exceeding 60 mph, making delivery feel like teleportation. The company aims to eliminate emissions, reduce traffic congestion, and dramatically lower last-mile delivery costs.

Positron develops AI inference hardware and systems designed to deliver lower-cost, lower-power deployment for large language models and other modern AI workloads.

Builds the world's most advanced ductless heat pump for residential use with integrated AI that identifies heating and cooling patterns to optimize efficiency.

AI-powered construction takeoff, cost estimation, and procurement platform delivering 90% faster takeoffs and 95% accuracy for subcontractors, general contractors, and developers.

Radiant is pioneering mass-produced portable nuclear microreactors, with its flagship Kaleidos reactor delivering 1 MW of clean, zero-emission power in a shipping container-sized form factor. Valued at $1.8 billion, the company is building its factory in Oak Ridge, Tennessee.

South Korean AI chip company developing neural processing units (NPUs) for AI inference workloads. Offers AI accelerators, chiplets, interconnects, and software stacks for large-scale deployments.

Provides AI-powered mapping tools like Farsight to help defense teams generate 3D terrain and plan missions.

Frontier AI research lab building next-generation AI models for semiconductor design. Develops recursive self-improvement cycle where AI designs silicon that powers the next generation of AI. Founded by AlphaChip creators from Google DeepMind.

Developer of the world's first DC data centers built exclusively for solar and wind power. Using proprietary chip design and smart controllers, Rune converts stranded and curtailed renewable energy into compute power at generation sites.

Science Corporation is a neural engineering company developing brain-computer interface (BCI) technology to restore and enhance human vision. The company's PRIMA retinal implant uses advanced neurotechnology to treat blindness caused by conditions like age-related macular degeneration, Stargardt disease, and retinitis pigmentosa. Founded by Neuralink co-founders Max Hodak and Alan Mardinly, Science has raised $489 million and is racing to become the first BCI company with a product in market.

Sennos builds AI software for fluidics and fermentation operations, focusing on process monitoring, optimization, and bioprocess analytics.

Vertically integrated electrical wire harness manufacturing platform for complex industrial supply chains.

Automation technology provider for fish processing industry using sensor fusion, edge computing, and machine learning for humane seafood processing

SIMULATE is a food technology company that manufactures plant-based chicken alternatives including NUGGS nuggets, DISCS patties, and chicken breast products, positioning itself as the 'Tesla of chicken' with a software-update approach to iterating on plant-based protein formulations. Founded in 2018, the company was acquired by Ahimsa Companies in October 2024 and is undergoing a revitalization of its brand and product lines.

Skyryse develops SkyOS, a universal operating system for flight, and is bringing software-defined avionics and autonomy to existing and new aircraft platforms.

Standard Nuclear is the country's first independent TRISO fuel manufacturer, providing reactor-agnostic nuclear fuel production to strengthen the advanced reactor supply chain.

Stoke Space Technologies develops the fully and rapidly reusable Nova rocket designed to operate with aircraft-like frequency. Founded by former Blue Origin and SpaceX employees, raised over $1.3B.

Substrate is America's next-generation semiconductor foundry, developing advanced X-ray lithography technology to challenge industry giants like ASML and TSMC. Founded by brothers James and Oliver Proud, the company uses compact particle accelerators to enable more cost-effective and rapid chip manufacturing in the United States. Backed by Founders Fund, General Catalyst, and In-Q-Tel, Substrate aims to restore American leadership in semiconductor production.

Sunday is a robotics company building Memo, a household humanoid robot designed to assist families with everyday chores like dishes, laundry, and tidying. Founded by Stanford-trained roboticists Tony Zhao and Cheng Chi, the company uses data from thousands of real homes to train its robots. Sunday reached a $1.15 billion valuation with its Series B round and is preparing to deploy its first robots through a Founding Family Beta program.

Sunflower Labs builds autonomous drone-based security systems that combine robotics, sensors, and software to monitor residential, commercial, and industrial properties.

Sunrise Robotics builds intelligent robotic cells for manufacturing, combining AI software, computer vision, and industrial automation to take repetitive work off factory floors.

Sway is a material innovation company that harnesses seaweed to create home-compostable replacements for single-use plastic packaging. Their patent-pending TPSea resin is 100% biobased and microplastic-free. Named TIME Best Invention of 2025.

Syenta develops Localized Electrochemical Manufacturing (LEM) technology for advanced semiconductor chip packaging, enabling scalable, high-density interconnects without traditional lithography. Spun out from the Australian National University, their approach addresses memory bandwidth bottlenecks in AI computing.

Electric vehicle manufacturer building compact city-friendly trucks starting with the MT1 model, combining utility vehicle functionality with sustainable electric power for urban and commercial use.

Terraforming robotics company that uses autonomous subsurface injection robots to lift and stabilize flood-prone terrain by injecting wood slurry deep underground, addressing urban flooding and land subsidence caused by sea level rise, extreme weather, and groundwater withdrawal with minimal surface disturbance.

The Nuclear Company operates as America's deployment platform for nuclear power, constructing a series of nuclear power plants using a design-once, build-many approach with proven and licensed technology to deliver safe and reliable electricity at the lowest cost.

Wi-Fi landline phone for kids and families that reinvents the home phone experience without screens, apps, or texting. Features parental controls via companion app to approve contacts, set quiet hours, and enable Do Not Disturb. Priced at $75 with free calling between Tin Cans or $10/month for regular phone numbers. Addresses smartphone addiction concerns and went viral, selling out first two production runs.

Building America's next generation of power infrastructure with hybrid inertial-battery systems combining mechanical flywheels with battery duration, providing grid stabilization without combustion or chemicals.

Unlimited Industries is an AI-native construction company that vertically integrates design and build for large-scale infrastructure projects including data centers, energy facilities, and advanced manufacturing. The company's proprietary AI platform can explore tens of thousands of design configurations to optimize costs and timelines, reducing pre-construction engineering from months to weeks. Founded by serial entrepreneurs and backed by Andreessen Horowitz, Unlimited is rethinking how America's critical infrastructure gets built.

Until Labs develops reversible cryopreservation technology to pause biological time, starting with organ-scale preservation to extend the viability of donor organs for transplantation. The company is building medical infrastructure toward whole-body medical hibernation technology.

Leisure-enhancing sunscreen brand based in Miami that creates the world's best-smelling sunscreen products with nostalgic appeal, sold nationwide through Ulta Beauty, Nordstrom, Anthropologie, BlueMercury, and Aerie, building a lifestyle brand around sun protection and leisure culture.

Nuclear energy innovation company developing advanced reactor prototypes using silicon carbide technology for next-generation nuclear power

VulcanForms is an advanced digital manufacturing company using metal additive manufacturing, precision machining, and automation to build industrial-scale production capabilities.

Z Modular designs and manufactures offsite modular building systems for multifamily, hospitality, and commercial construction projects.

Zoo builds AI-native CAD infrastructure for hardware engineers, offering a browser-based design studio, programmable geometry tooling, and agentic workflows for creating manufacturing-ready 3D models.