Manufacturing AI Startup Jobs

CesiumAstro builds communications systems and phased-array hardware/software for space, air, and ground missions, supporting satellite and defense connectivity use cases.

K2 Space designs and manufactures large, high-power "mega-class" satellites with enhanced payload capacity and propulsion for government and commercial customers. The company is vertically integrated, building its satellites at a factory in Torrance, CA, with additional teams in Seattle, Los Angeles, and Washington DC.

Formlabs designs and manufactures professional-grade 3D printing systems, including stereolithography (SLA) and selective laser sintering (SLS) printers, materials, and software. Based in Somerville, MA, the company serves engineering, manufacturing, dental, and design customers worldwide.

Form Energy develops iron-air battery technology for multi-day, utility-scale energy storage, with R&D and engineering in Somerville, MA and Berkeley, CA and a manufacturing plant (Form Factory 1) in Weirton, WV. The company has raised over $1.2B across multiple rounds including a $405M Series F in October 2024.

Scout Motors is a Volkswagen-owned American vehicle brand reviving the Scout nameplate to build electric and range-extended SUVs and pickup trucks. The company is building a $2B+ production facility in Blythewood/Columbia, SC, with additional offices in Charlotte, NC, Fremont, CA, and Novi, MI.

Celonis is a leading process mining and execution management platform that ingests data from enterprise systems (ERP, CRM, etc.) to visualize, analyze, and automate business processes. Headquartered in Munich and New York, it serves large enterprises across manufacturing, supply chain, and finance operations. The company is a decacorn last valued around $13B via secondary market transactions.

Vast is a US-based commercial space company building human-rated artificial-gravity orbital space stations, starting with its single-module Haven-1 station targeted as the world's first commercial space station. Founded by Jed McCaleb and headquartered in Long Beach, California ('Space Beach'), the company designs and manufactures its spacecraft hardware in-house. It is racing to provide a commercial successor to the International Space Station.

Base Power is building America's next-gen power company by deploying whole-home battery backup systems that protect families from outages and strengthen the grid. Deployed over 100MWh of residential battery capacity.

Autonomous drone manufacturer building AI-powered drones for defense, public safety, and enterprise inspection.

Atoms is Travis Kalanick's physical-AI and industrial robotics holding company, rebranded in March 2026 from City Storage Systems. It operates business units across food (CloudKitchens, Otter, Lab37, Picnic), autonomous mining (built on acquired robotics firm Pronto), and transport, building a shared robotics 'wheelbase' for specialized industrial machines rather than humanoids. The company runs operations in 110+ cities and raised $1.7B led by a16z in July 2026, with Ben Horowitz joining the board.

A defense technology company specializing in counter-drone radar and other defense solutions.

Muon Space is an end-to-end satellite constellation company that designs, builds, and operates mission-optimized spacecraft delivering Earth intelligence data for climate monitoring, weather, and national security customers including the NRO and Space Force.

Apex is a defense-grade satellite bus manufacturer producing configurable, productized spacecraft platforms (Aries, Nova, Comet) for LEO, MEO, and GEO orbits. The Los Angeles-based company serves commercial and sovereign government customers at scale with peak annual capacity exceeding 200 units per year. Apex launched Project Shadow, the first commercially-led on-orbit space-based interceptor demonstration.

Divergent Technologies develops the Divergent Adaptive Production System (DAPS), an end-to-end digital manufacturing platform that uses machine learning to design, 3D-print, and automate assembly of complex vehicle structures. Based in Torrance, CA, it serves automotive OEMs (Aston Martin, Bugatti, McLaren) and is expanding into aerospace and defense (Lockheed Martin, General Atomics, Raytheon).

Hadrian builds AI-enabled autonomous factories that manufacture precision components and systems for aerospace, defense, shipbuilding, and other industrial customers, combining software, robotics, machining, inspection, and factory operations.

Redwood Materials builds a circular supply chain for lithium-ion batteries, recycling end-of-life batteries and production scrap, refining critical elements like lithium, nickel, and cobalt, and manufacturing battery materials domestically. It also deploys large-scale energy storage systems using second-life EV battery packs. Founded by former Tesla CTO JB Straubel, it operates facilities in Nevada and South Carolina.

General Matter is rebuilding domestic uranium enrichment capacity in the U.S., developing low-enriched and high-assay low-enriched uranium to support advanced nuclear power and American energy security.

Commonwealth Fusion Systems is an MIT spinout developing commercial fusion energy, building the SPARC demonstration tokamak in Devens, MA and the ARC commercial power plant in Virginia. It has raised roughly $4 billion to date, including a $1 billion round in July 2026 from pension funds, sovereign wealth funds, and infrastructure investors.

Varda Space Industries builds autonomous spacecraft that manufacture pharmaceuticals and other materials in microgravity before returning them to Earth, and sells orbital reentry and hypersonic-test services to government and commercial customers. Founded in 2021 by Will Bruey and Delian Asparouhov, the El Segundo-based company became a unicorn after its 2026 Series D.

Etched is an American semiconductor startup building Sohu, an ASIC purpose-built for transformer inference rather than general-purpose GPU compute. The company co-designs chips, racks, system software and manufacturing into full frontier inference clusters optimized for both prefill and decode workloads. Founded by Harvard dropouts in 2022, it raised a $300M Series C in July 2026 at a $10.3B valuation to scale production against Nvidia.

Neros designs and manufactures high-performance attritable FPV drones and ground control systems for the U.S. military and allied forces, building a vertically integrated, China-free supply chain. Founded in 2023 by former professional drone racers, it has scaled rapidly to supply the U.S. Army, Marine Corps, and Ukraine.

Nuclear energy innovation company developing advanced reactor prototypes using silicon carbide technology for next-generation nuclear power

Radiant is pioneering mass-produced portable nuclear microreactors, with its flagship Kaleidos reactor delivering 1 MW of clean, zero-emission power in a shipping container-sized form factor. Valued at $1.8 billion, the company is building its factory in Oak Ridge, Tennessee.

1X Technologies builds general-purpose humanoid robots designed for home and industrial use. Their flagship products include EVE for industrial facilities and NEO for the home. Backed by OpenAI.

Figure develops general-purpose humanoid robots and embodied AI systems for industrial and logistics environments, combining robotics hardware with AI control systems.

Harbinger designs and manufactures purpose-built electric and hybrid chassis for medium-duty commercial vehicles such as delivery trucks and RVs. The company has secured a FedEx order and investment as part of its Series C round.

Antares is developing mass-producible, inherently safe nuclear microreactors for terrestrial, underwater, and space-based applications, producing between 100 kilowatts and 1 megawatt of electricity. The company has a 145,000-square-foot manufacturing facility in Torrance, California and is on track to achieve first reactor criticality by mid-2026. Founded by alumni of SpaceX, MIT, and Los Alamos National Lab, Antares is backed by over $130 million in venture capital and government funding.

Inversion Space is turning space into a transportation layer for Earth by building autonomous re-entry vehicles that enable precision delivery of cargo to anywhere on the planet in under an hour, creating an on-demand logistics network in Low-Earth Orbit.

Northwood Space designs and manufactures electronically steered phased-array ground stations that enable scalable, rapidly deployable satellite communication and tracking infrastructure. The company serves commercial and government customers including a $50M U.S. Space Force contract to modernize the Satellite Control Network.

Stoke Space Technologies develops the fully and rapidly reusable Nova rocket designed to operate with aircraft-like frequency. Founded by former Blue Origin and SpaceX employees, raised over $1.3B.

The Nuclear Company operates as America's deployment platform for nuclear power, constructing a series of nuclear power plants using a design-once, build-many approach with proven and licensed technology to deliver safe and reliable electricity at the lowest cost.

Develops factory-fabricated modular nuclear microreactors designed for AI data centers and industrial applications. The Aalo Pod is a 50 MWe power plant purpose-built for data centers.

Vertically integrated home electrification company deploying affordable all-electric heat pump systems across North America, reducing upgrade costs up to 50% with over 1,000 installations to date

VulcanForms is an advanced digital manufacturing company using metal additive manufacturing, precision machining, and automation to build industrial-scale production capabilities.

Vulcan Elements manufactures sintered neodymium iron boron rare earth magnets at its Research Triangle Park, North Carolina facility, aiming to build a U.S. supply chain independent of China. Founded in 2023, the company serves defense and commercial customers including the U.S. military branches.

Amca (Advanced Manufacturing Company of America) acquires and modernizes domestic factories to produce certified aerospace and defense components, combining engineering, qualification testing, and manufacturing on its RAPID AI platform. Based in El Segundo, California, it supplies parts for the F-35, F-16, M1 Abrams, and commercial aircraft to primes like Lockheed Martin, Boeing, and Honeywell.

Osmo uses AI-powered olfactory intelligence to digitize and generate custom scent formulas, building the world's first AI-powered fragrance house with robotic production capabilities.

ALSO. is an electric mobility company spun out of Rivian that is building small, vertically integrated EVs for dense urban movement and autonomous delivery. Its vehicles combine new propulsion, software, and hardware to replace short car trips with lighter electric transport.

Eight Sleep builds connected sleep technology, most notably the Pod — a smart mattress cover that uses biometrics, AI, and dynamic temperature control to optimize sleep. The company is expanding from consumer sleep fitness into predictive, AI-driven health and medical applications such as sleep apnea detection. It is a New York-based unicorn valued at $1.5B.

PhysicsX is an AI company accelerating industrial innovation by combining AI-driven multiphysics inference with numerical simulation to improve the design, manufacturing, and operation of complex products. Founded in 2019 by former Formula 1 engineers, the platform serves enterprises across aerospace, defense, automotive, semiconductors, and energy sectors. PhysicsX raised over $155M including investments from NVIDIA, Atomico, and Temasek.

Standard Bots builds AI-native industrial robot arms and the software stack that runs them, targeting manufacturers who want automation without dedicated robotics engineers. Its RO1 cobot combines a no-code/AI control interface with US-based manufacturing in Glen Cove, NY. The company hit a $1B valuation with a $200M Series C in June 2026.

Mytra develops automated robotic storage and warehouse automation solutions using bots, software, and modular cells. The platform features AI-optimized dynamic pathways, slotless inventory management, and a three-dimensional grid system for storing and moving materials in warehouses. Founded by ex-Tesla and Rivian leaders.

Building vertically integrated, automated metal factories in Detroit that deliver raw materials faster, cheaper, and more reliably to US manufacturers. Software-driven quoting in milliseconds.

Robotics AI company building foundation models for general-purpose robots to handle physical world interactions with advanced manipulation capabilities

Building America's next generation of power infrastructure with hybrid inertial-battery systems combining mechanical flywheels with battery duration, providing grid stabilization without combustion or chemicals.

Designs and fabricates superconducting quantum processors at industrial scale using its open VIO architecture, serving 50+ customers across 20 countries.

RobCo is a Munich-founded industrial robotics startup providing modular, plug-and-play robotic hardware kits and AI-powered automation software for small and mid-sized manufacturers. Its RobCo Studio software enables no-code programming of robots for tasks like machine tending, palletizing, welding, and dispensing. Backed by Lightspeed and Sequoia, it is scaling US operations with offices in San Francisco and Austin.

TerraFirma is an Austin-based, vertically integrated construction robotics company founded in 2024 by former SpaceX engineers Noah Schochet (CEO) and Noah McGuinness (CTO). It retrofits heavy equipment — excavators, dozers, loaders, rollers, skid steers — for AI-assisted remote and semi-autonomous operation, paired with AI construction planning software. Rather than only selling robots to contractors, TerraFirma takes on earthwork, demolition, site prep, and infrastructure projects itself for data centers, roads, substations, and energy sites.

BRINC Drones builds public-safety drone systems for 911 rapid response, indoor tactical operations, firefighting, and search and rescue, including the Lemur 2, Responder, and Guardian aircraft plus its LiveOps command-and-control software. Its platform integrates with Motorola Solutions' police radios, 911/CAD, and CommandCentral systems and is used by 900+ public-safety agencies and more than 20% of U.S. SWAT teams. Founded by CEO Blake Resnick and headquartered in Seattle, the company is scaling U.S. manufacturing with a new Queen Anne factory and HQ.

Fuse Energy Technologies builds pulsed-power machines (Marx generators like TITAN) for magnetized liner inertial fusion (MagLIF), generating near-term revenue from nuclear-effects radiation testing for the NNSA, national labs, and defense agencies while working toward commercial fusion power. Founded in 2019 by JC Btaiche and headquartered in San Leandro, CA.

Machina Labs develops AI-powered robotic manufacturing systems for sheet metal forming and industrial production, reducing the need for traditional tooling.

Ernesta is a direct-to-consumer brand selling custom-sized rugs through an ecommerce platform paired with a growing network of physical showrooms and an in-house fabrication facility. Founded in 2022 by Peloton co-founder John Foley, it positions itself as the largest custom-sized rug retailer in the U.S. It has raised venture funding across Seed, Series A, and Series B rounds led by Addition.

Monumental develops AI-powered autonomous robots for on-site masonry construction work, performing bricklaying with millimeter precision using computer vision to make construction software-defined and autonomous.

Dyna Robotics develops high-performance general-purpose robots powered by proprietary embodied AI foundation models that achieve 99+ percent success rates in commercial environments with self-improving capabilities.

Orchard builds AI-powered robotic systems that automate orchard harvesting with computer vision and advanced robotics.

Sunday is a robotics company building Memo, a household humanoid robot designed to assist families with everyday chores like dishes, laundry, and tidying. Founded by Stanford-trained roboticists Tony Zhao and Cheng Chi, the company uses data from thousands of real homes to train its robots. Sunday reached a $1.15 billion valuation with its Series B round and is preparing to deploy its first robots through a Founding Family Beta program.

Voltai builds foundation models and AI agents for the semiconductor and electronics industry, aiming to let AI reason about and design physical hardware. Its systems run large-scale simulation to assist with chip design, verification, and EDA workflows for semiconductor, consumer electronics, and automotive customers. Founded by former Stanford professors and SAIL researchers alongside ex-CTOs from Synopsys and GlobalFoundries, the company is based in Palo Alto, CA.

Watney builds dual-armed robots that perform physical maintenance work inside hyperscale AI data centers, such as cable swaps and server restarts. Founded in San Francisco in 2023 by Ryan Gannon and Sean Cheong, it has been testing robots with Meta since 2025 and operates the largest fleet of dexterous robots running 24/7/365 across the United States.

CoLab Software builds an AI-powered Design Engagement System (EngineeringOS) that helps mechanical and hardware engineering teams collaborate on CAD designs, conduct design reviews, and apply AI-driven checks (AutoReview) to accelerate product development. Customers include Johnson Controls and Ford. The platform turns every review into a structured, searchable knowledge base for engineering teams.

Efficient Computer builds the world's most energy-efficient general-purpose processor, the Electron E1, offering up to 100x greater efficiency than traditional CPUs. Spun out of Carnegie Mellon University, their Fabric architecture minimizes data movement, enabling applications in AI, edge computing, space, defense, and consumer devices.

Mythic builds power-efficient analog compute technology for AI inference, targeting edge-to-enterprise deployments where energy efficiency and throughput are critical.

Pacific Fusion is building a high-gain pulsed magnetic fusion system designed to achieve net facility gain, delivering more fusion energy output than all stored energy input. The company develops affordable, modular fusion technology using common materials to provide abundant, clean energy for a prosperous planet.

Airbound builds the world's most efficient delivery drones, developing advanced autonomous aircraft using blended-wing-body designs for ultra-low-cost logistics. Founded by 20-year-old Naman Pushp, the Bengaluru-based company aims to achieve one-cent drone deliveries at scale, serving medical, defense, and industrial applications.

Normal builds AI systems and thermodynamic computing hardware to accelerate semiconductor design and improve energy efficiency in compute. The company works with large chip and manufacturing partners while developing its own next-generation computing architecture.

Vertically integrated electrical wire harness manufacturing platform for complex industrial supply chains.

A robotics company providing robotic solutions for wind turbine blade maintenance and inspection, using specialized robots for cleaning, coating, and repair.

Robotics company using wall-climbing robots and AI for industrial inspections and predictive maintenance.

Skyryse develops SkyOS, a universal operating system for flight, and is bringing software-defined avionics and autonomy to existing and new aircraft platforms.

Atomic Industries is an AI-powered tool-and-die manufacturer that applies machine learning to modernize precision manufacturing.

Neurophos is an Austin-based semiconductor startup developing photonic AI inference chips, spun out of metamaterials research at Duke University. Its Optical Processing Unit (OPU) compresses rack-scale AI compute into a single package using CMOS-compatible photonic tensor cores, targeting the compute-bound prefill stage of inference.

Taara develops free-space optical communication technology that delivers high-speed connectivity through narrow beams of light instead of fiber or radio spectrum. Spun out of X, Alphabet's Moonshot Factory, the company builds optical wireless systems and photonics technology for expanding broadband infrastructure.

Arbor Energy develops supercritical CO2 turbines that deliver clean, carbon-negative power through fuel-flexible technology optimized for AI data centers and industrial applications.

Elveo Mobile (formed in 2026 by the merger of Lynk Global and Omnispace) operates a satellite direct-to-device (D2D) network that connects standard, unmodified mobile phones directly to low-Earth-orbit satellites, combining Lynk's D2D platform with Omnispace's S-band spectrum.

Nexxa builds specialized AI agents that automate complex technical workflows in heavy industries using multi-agent architecture and computer use capabilities.

Frontier AI company on a mission to solve breakthrough materials discovery using generative AI and advanced molecular simulations, compressing decades of R&D into months.

Semiconductor company pioneering chiplet interconnect technologies to unleash the performance of AI chips, backed by AMD, Arm, Meta, Samsung and Intel Capital

RoboForce builds AI-enabled mobile manipulation robots ('Robo-Labor') that perform dangerous, repetitive industrial work in solar installation, mining, data centers, manufacturing, and logistics. Founded in 2023 by veterans of CMU, Amazon Robotics, Waymo, Cruise, and Tesla, it is developing its RF-04 robot and TITAN platform for large-scale deployment.

Wi-Fi landline phone for kids and families that reinvents the home phone experience without screens, apps, or texting. Features parental controls via companion app to approve contacts, set quiet hours, and enable Do Not Disturb. Priced at $75 with free calling between Tin Cans or $10/month for regular phone numbers. Addresses smartphone addiction concerns and went viral, selling out first two production runs.

Catalyx Space builds orbital logistics infrastructure, combining spacecraft, software, and operations to move experiments and manufactured payloads to orbit and back. The company focuses on reusable capsules and faster, more predictable in-space deployment and downmass services.

Last Energy designs, builds, owns, and operates micro-modular nuclear power plants, most notably the PWR-20, a factory-built 20 MWe pressurized water reactor delivered as pre-fabricated modules. It sells full-service on-site baseload power to data centers, industrial facilities, and utilities, and is building a 5 MW pilot reactor at the Texas A&M-RELLIS campus. Spun out of the Energy Impact Center in 2019 by founder Bret Kugelmass, it is now headquartered in Austin, Texas.

Defense technology company providing software platform for military logistics and field operations optimization.

Westmag (Western Magnetics Company) designs and manufactures drone motors and robot actuators at Factory 01 in South San Francisco, aiming to build a vertically-integrated, NDAA-compliant American supplier for the physical AI hardware stack. The company exited stealth in June 2026 after closing an $11M seed round led by Andreessen Horowitz with participation from Founders Fund, Lux Capital, NFDG, and Menlo Ventures.

Bright Machines provides software-defined manufacturing and industrial automation systems that combine robotics, AI, and computer vision for electronics production.

Kepler Communications is a Toronto-based satellite connectivity operator building a global low-Earth orbit constellation for broadband and IoT connectivity. The company deploys optical inter-satellite links and is expanding into orbital AI compute via Nvidia Orin chips. Founded in 2015, Kepler has raised over $177M to connect space-borne and ground assets worldwide.

Medra develops autonomous AI-powered robotic scientists that run and refine laboratory experiments end-to-end, interfacing with standard lab tools to accelerate drug discovery and biological research.

Axion (formerly Axion Ray) is an AI-powered quality intelligence platform for manufacturers. It unifies field, service, and design data to detect, investigate, and resolve product quality issues earlier and cut root-cause analysis time. Customers span industrial, aerospace, consumer, and medtech manufacturing, including Daikin, Harley-Davidson, and SharkNinja.

A cloud-based software platform designed for commercial contractors (MEP, Fire Life and Safety) to manage projects, field service, job costing, and scheduling in an all-in-one solution.

Charge Robotics builds autonomous robots that construct solar farms through the Sunrise system, a portable robotic construction unit that automates the assembly and installation of solar-tracking hardware, making renewable energy deployment faster and more cost-effective.

Colossal Biosciences is a genetic engineering and de-extinction company using CRISPR technology to restore extinct species like the woolly mammoth and protect critically endangered ecosystems.

Frontier AI research lab building next-generation AI models for semiconductor design. Develops recursive self-improvement cycle where AI designs silicon that powers the next generation of AI. Founded by AlphaChip creators from Google DeepMind.

Architect Labs builds AI systems that design and formally verify custom silicon, turning demanding workloads into purpose-built chips and full-stack hardware solutions. It partners with enterprises, AI labs, and governments to dramatically accelerate custom chip development timelines. Founded by Ebrahim Hussain and Aaditya Subedi (incorporated as Architect Silicon Inc.), it emerged from stealth in June 2026 with a $24M seed round led by Kindred Ventures.

Fortastra builds intelligent, maneuverable spacecraft designed to protect government and commercial satellites through remote sensing, autonomous capabilities, and defensive rendezvous and proximity operations. The company targets satellite security, space infrastructure resilience, and operational risk in contested orbital environments. It is headquartered in Torrance, California.

Construction management software providing contractors with time tracking, payroll, compliance, and payment solutions for construction workflows

Sunrise Robotics builds intelligent robotic cells for manufacturing, combining AI software, computer vision, and industrial automation to take repetitive work off factory floors.

Carbon Robotics develops AI-powered agricultural robotics, including its flagship LaserWeeder which uses computer vision, deep learning, and CO2 lasers to identify and eliminate weeds with millimeter accuracy. The company also offers Carbon ATK, a tractor autonomy solution, and operates across 15 countries supporting over 100 crop types. Founded in 2018 and headquartered in Seattle.

Olipop is a prebiotic soda brand creating healthier alternatives to traditional sodas, using plant fiber and botanicals to support digestive health while delivering classic soda flavors.

Oxide Computer Company builds rack-scale cloud computing infrastructure for enterprises that need the agility of public cloud with the control and security of on-premises hardware. Their integrated hardware-software platform delivers a complete cloud experience in a single rack unit.

Terraforming robotics company that uses autonomous subsurface injection robots to lift and stabilize flood-prone terrain by injecting wood slurry deep underground, addressing urban flooding and land subsidence caused by sea level rise, extreme weather, and groundwater withdrawal with minimal surface disturbance.

Extropic is building thermodynamic computing hardware and software for radically more energy-efficient AI workloads. The company combines physics, chip design, and systems engineering to develop new compute architectures for next-generation intelligence.

Lightship is the first American all-electric recreational vehicle company, designing and producing aerodynamic, battery-powered travel trailers. Founded by Tesla alumni, the company builds zero-emission travel trailers including the Atmos and Panos models, with deliveries starting in 2026. Lightship is headquartered in Broomfield, Colorado.

Mercura provides AI-powered quoting and order automation for distributors and manufacturers in HVAC, electrical, and plumbing industries, extracting RFQs from emails and calls to generate accurate quotes and sync with ERPs. Backed by Y Combinator (W25), the Munich-based company serves 60+ distributors and manufacturers.

Omen AI builds miniaturized spectroscopic sensors that continuously monitor coolant, oil, and water in AI data centers and industrial machinery, detecting contamination and equipment wear in real time. Its hardware replaces the industry's slow lab-sampling process, helping operators avoid costly cooling-loop failures in liquid-cooled AI infrastructure.

Positron develops AI inference hardware and systems designed to deliver lower-cost, lower-power deployment for large language models and other modern AI workloads.

Builds the world's most advanced ductless heat pump for residential use with integrated AI that identifies heating and cooling patterns to optimize efficiency.

Unlimited Industries is an AI-native construction company that vertically integrates design and build for large-scale infrastructure projects including data centers, energy facilities, and advanced manufacturing. The company's proprietary AI platform can explore tens of thousands of design configurations to optimize costs and timelines, reducing pre-construction engineering from months to weeks. Founded by serial entrepreneurs and backed by Andreessen Horowitz, Unlimited is rethinking how America's critical infrastructure gets built.

Zanskar is an AI-powered geothermal exploration company that uses custom-built machine learning models to discover untapped conventional geothermal resources. The platform combines seismic characterization, directional drilling guidance, and reservoir modeling, and develops utility-scale geothermal power plants across the western United States.

Chef Robotics builds AI-enabled robotic systems for food factories, prepared-meal production, and food assembly operations. Its robots automate repetitive plating, portioning, and packaging tasks in commercial food production, offered via a Robotics-as-a-Service model. The company has deployed systems that have produced tens of millions of meals.

Flexion Robotics builds the brain for humanoid robots with an AI-driven reinforcement learning and sim-to-real autonomy platform founded by former Nvidia researchers powering humanoids across morphologies and tasks.

Gravis Robotics is a Zurich-based, ETH Zurich spinout that builds autonomous AI systems for heavy construction machinery. Its Gravis Rack retrofits excavators and other equipment from manufacturers like Caterpillar, John Deere, and Volvo to enable AI-assisted or fully autonomous operation on jobsites.

London-based direct-to-consumer fresh cat food platform delivering personalized nutrition, having served over 100 million fresh meals and captured 2% of the UK cat food market

A biotechnology company developing carbon-negative polymers and materials using genetically engineered enzymes.

Helm.ai develops AI software for autonomous driving (AD/ADAS) and robotics automation, using an unsupervised 'Deep Teaching' approach that trains neural networks without human annotation or simulation. It partners with major automotive OEMs, and in October 2025 received an additional strategic investment from Honda to accelerate next-generation AD/ADAS development.

Until Labs develops reversible cryopreservation technology to pause biological time, starting with organ-scale preservation to extend the viability of donor organs for transplantation. The company is building medical infrastructure toward whole-body medical hibernation technology.

Cresilon develops hemostatic medical devices, including gel-based technologies that rapidly stop bleeding for human and animal care.

Debut is a beauty biotechnology company that uses AI-powered ingredient discovery and biofermentation to create high-performing, sustainable beauty ingredients from molecules that nature produces only in minute quantities. Named one of TIME100 Most Innovative Companies in 2025, the company partners with major brands like L'Oreal to develop next-generation skincare actives with a focus on skin longevity. Headquartered in San Diego, Debut has raised over $89 million and screens billions of candidate molecules through its proprietary platform.

Grid Aero builds autonomous cargo aircraft for long-range, high-payload logistics solutions serving both military and commercial applications with rapid development cycles.

Substrate is America's next-generation semiconductor foundry, developing advanced X-ray lithography technology to challenge industry giants like ASML and TSMC. Founded by brothers James and Oliver Proud, the company uses compact particle accelerators to enable more cost-effective and rapid chip manufacturing in the United States. Backed by Founders Fund, General Catalyst, and In-Q-Tel, Substrate aims to restore American leadership in semiconductor production.

Cover designs and manufactures custom modular residential structures in a factory and assembles them on-site in weeks. The company uses proprietary design software and a steel-frame building system for ADUs and backyard homes.

Didero is a US-based AI procurement and supply-chain startup that builds agentic AI sitting on top of a company's existing ERP to automate core procurement workflows for manufacturers and distributors—supplier communication, order tracking, exception handling, and spend analysis. Founded in 2023 and based in New York, it is embedded with 30+ customers. In February 2026 it raised a $30M Series A co-led by Chemistry and Headline with participation from Microsoft's M12.

AI-driven manufacturing platform that automates the creation and management of model-based work instructions from CAD files. BuildOS generates 3D animations of assembly steps, reducing documentation time from weeks to hours.

Engineering general intelligence (“Archie”) that performs quantitative and spatial reasoning for physical engineering.

Electronic warfare company building AI-driven software and hardware—incl. SIGINT payloads and autonomous drones—for spectrum dominance.

AI analytics platform for building materials and home improvement manufacturers.

Dexterity develops physical AI robotic systems for industrial automation, enabling warehouses and logistics operations to automate complex manipulation tasks.

Ecorobotix is a Swiss agricultural technology company that develops AI-powered precision spraying systems, including the ARA field sprayer, which uses computer vision and machine learning to detect individual plants and apply herbicides with up to 95% less chemical usage. Founded in 2014 and headquartered in Yverdon-les-Bains, Switzerland, the company has deployed approximately 1,000 ARA units across Europe and operates in over 20 countries.

Resilience (National Resilience, Inc.) is a contract development and manufacturing organization (CDMO) providing end-to-end biomanufacturing for biologics, vaccines, cell and gene therapies. Founded in 2020 and headquartered in Blue Ash, Ohio, it operates multiple facilities across North America and has raised over $2.5B in equity financing.

Squint is an AI-powered manufacturing intelligence platform that helps industrial frontline operators reduce downtime and improve quality at scale. The platform delivers AR-guided procedures and knowledge-sharing tools to factory floors, serving customers like PepsiCo, Michelin, and Ford.

Sunflower Labs builds autonomous drone-based security systems that combine robotics, sensors, and software to monitor residential, commercial, and industrial properties.

Corvus Robotics builds fully autonomous warehouse inventory drones that scan, count, and track pallets without facility modifications or external infrastructure. Its Level 4 autonomous drones navigate aisles and read barcodes to automate inventory management for warehouses and manufacturing facilities. The company sells this inventory-and-inspection capability as a service to enterprise logistics operators.

Builds and operates automated drill rigs to accelerate mineral discovery, integrating autonomous control systems and real-time data streams into diamond core drilling for mineral exploration.

Intenseye provides an AI-powered computer vision platform that monitors workplace environments in real time to detect safety hazards and environmental, health & safety (EHS) risks. The platform integrates with existing camera infrastructure to help industrial and manufacturing companies prevent workplace injuries.

Morpheus Space develops electric propulsion systems and mobility solutions for satellites, including modular thrusters for commercial and government space missions.

Airloom Energy is reinventing wind power with a novel, low-profile track-based turbine system that dramatically reduces the cost and complexity of harnessing wind energy. Backed by Bill Gates' Breakthrough Energy Ventures and Lowercarbon Capital, the Laramie, Wyoming-based startup is developing a pilot facility to demonstrate its modular wind technology. Airloom's design uses lightweight airfoils on an oval track, offering a simpler and more affordable alternative to traditional wind turbines.

Climate tech company building a carbon-smart wood supply chain and marketplace for reclaimed timber.

Camfer is building an AI mechanical engineer that works on top of industry-standard CAD platforms such as SolidWorks and Onshape. Its product converts natural-language prompts or images into design artifacts — sketches, features, and assemblies — directly inside existing CAD workspaces. The Y Combinator-backed company targets hardware engineering and physical product workflows.

Building the world's most biomimetic musculoskeletal androids featuring over 200 degrees of freedom and proprietary artificial muscles. The Protoclone V1 can be manufactured for under $20,000.

Copper is a Berkeley-based startup that makes battery-equipped induction stoves that plug into regular 120V outlets, enabling easy upgrades from gas to induction without costly electrical work, combining premium cooking performance with grid-supporting battery technology.

Framework designs high-performance, modular laptops that are easy to upgrade, customize, and repair, creating consumer electronics products designed to last and reduce electronic waste.

Heirloom is a direct air capture company that accelerates limestone's natural ability to absorb carbon dioxide from the atmosphere, reducing the process from years to just days. The company has built facilities in California and Louisiana to permanently remove CO2 at scale, supporting the global effort to combat climate change. Backed by Breakthrough Energy Ventures and Lowercarbon Capital, Heirloom is one of the leading carbon removal technology providers.

Pipedream Labs is building an autonomous underground delivery network using robotic carts that travel through buried tubes at speeds exceeding 60 mph, making delivery feel like teleportation. The company aims to eliminate emissions, reduce traffic congestion, and dramatically lower last-mile delivery costs.

Sudo Robotics is building general-purpose robots powered by a manipulation-centric foundation model, with its flagship #sudo R1 system integrating self-developed hardware and software. The system trains manipulation policies in simulation alone, using reactive observation-conditioned control at 15-25 Hz to achieve high reliability in object picking and grasping. The company targets physical-AI applications across manufacturing, logistics, agriculture, and eldercare.

Zoo builds AI-native CAD infrastructure for hardware engineers, offering a browser-based design studio, programmable geometry tooling, and agentic workflows for creating manufacturing-ready 3D models.

Hanomi builds AI software for mechanical engineering teams, turning 3D CAD models into production-ready drawings and structured manufacturing knowledge.

Provides AI-powered mapping tools like Farsight to help defense teams generate 3D terrain and plan missions.

Syenta develops Localized Electrochemical Manufacturing (LEM) technology for advanced semiconductor chip packaging, enabling scalable, high-density interconnects without traditional lithography. Spun out from the Australian National University, their approach addresses memory bandwidth bottlenecks in AI computing.

Cellares is an integrated development and manufacturing organization (IDMO) for cell therapies, using automation and industrial-scale manufacturing systems to expand access to life-saving treatments.

Flash-frozen specialty coffee capsule company that delivers barista-quality coffee to consumers, requiring no machine — just add water or milk to enjoy.

Home electrification company accelerating decarbonization with next-generation battery-integrated induction appliances for sustainable homes

Infinite Machine designs and manufactures premium electric non-car vehicles for urban transportation, combining distinctive hardware, connected software, and vehicle services around products such as P1 and Olto.

Kingdom Supercultures engineers microbes to create functional ingredients for food and beverage brands.

Osium AI builds an AI platform for materials and chemicals R&D, helping industrial teams accelerate discovery, formulation, and optimization workflows.

Leisure-enhancing sunscreen brand based in Miami that creates the world's best-smelling sunscreen products with nostalgic appeal, sold nationwide through Ulta Beauty, Nordstrom, Anthropologie, BlueMercury, and Aerie, building a lifestyle brand around sun protection and leisure culture.

Applied Atomics is a US-based deep-tech startup that develops and operates full-stack nuclear power plants (100MW–1GW) for industrial customers, delivering dispatchable, carbon-free electricity through long-term power purchase agreements. Founded by former SpaceX and aerospace leaders, it vertically integrates Gen III+ reactor technology with in-house plant engineering, supply chain, and operations to speed deployment and lower cost. It raised an $8.3M Seed round in March 2026 led by Transition, bringing total funding to roughly $12M.

Arena Physica (formerly Arena/Arena.ai) is a New York-based AI hardware engineering company building 'electromagnetic superintelligence.' Its Atlas platform and Heaviside physics-native foundation model predict electromagnetic behavior from design geometry in milliseconds, helping customers like AMD, Anduril, and Sivers Semiconductors design, test, and validate hardware across semiconductors, aerospace, automotive, and defense.

Armstrong Robotics builds general-purpose robots for commercial kitchens, starting with AI-powered dishwashing automation that handles messy, unpredictable environments with commercial-grade reliability. Its systems use robot arms with 3D perception trained on thousands of hours of real dishwashing data and integrate with existing commercial dish machines on a subscription model. The platform is designed to extend to other repetitive kitchen tasks beyond dishwashing.

AstroForge is a deep-space mining company focused on extracting valuable metals from asteroids, particularly platinum group metals (PGMs) and critical minerals. The company develops technology to locate, reach, and mine asteroids to provide sustainable resources for Earth and space industries.

Astrus is an AI-powered microchip design company that develops software to automate analog chip layout design. The platform uses reinforcement learning to help circuit designers create advanced microchips, learning semiconductor physics and balancing performance with manufacturability. The company is based in Toronto and Waterloo, Canada.

Augrade is an AI-powered spatial computing platform that automates heavy industry design and engineering, generating manufacturing and construction-grade CAD models in minutes.

Fusion energy startup developing modular micro-fusion reactors for compact, scalable clean power and propulsion applications.

Axiom Space is a Houston-based commercial space infrastructure company building the world's first fully commercial space station, Axiom Station, as a successor to the ISS. It also conducts private astronaut missions to the ISS and develops the AxEMU next-generation spacesuit under a NASA contract.

Axis Robotics builds a distributed data engine for physical AI, letting a global network of contributors generate robot training data through browser-based teleoperation and mobile collection tools. Its simulation-first stack combines large-scale pretraining data, hybrid augmentation, and corrective post-training feedback into a continuously improving loop for embodied AI models. The network claims 100,000+ contributors producing roughly 1,200 hours of simulation and 20,000 hours of real-world data monthly, with commercial partners including Booster Robotics and Geely Auto.

Ayar Labs builds optical I/O and in-package photonics technology to reduce data-movement bottlenecks in large-scale AI and high-performance computing systems.

Backflip AI turns text prompts into 3D models and design-ready assets for physical products.

Blue Origin is Jeff Bezos's private aerospace company developing rockets, spacecraft, and lunar landers for commercial, government, and civil space missions. It operates New Shepard suborbital flights and is developing the orbital New Glenn rocket and Blue Moon lunar lander.

Boom Supersonic is a Colorado-based aerospace company building Overture, a Mach 2.2 commercial supersonic airliner. It has also expanded into natural-gas turbines (Superpower) for data-center power, including an order from Crusoe.

The Boring Company designs and builds underground tunnel infrastructure for rapid transit and utilities, with operations including a manufacturing facility in Bastrop, TX. It has raised $917M in total funding from investors including Founders Fund, Sequoia, and 8VC.

BotBuilt develops robotics and automation systems for homebuilding, including robotic framing workflows to improve speed and labor efficiency.

A venture-backed defense tech company building mass-producible hypersonic weapons systems using modern hardware development and manufacturing processes.

Cerrion is a Zurich-based industrial-AI company that turns standard factory cameras into 24/7 AI video agents which detect process deviations, quality defects, and safety issues on production lines and intervene automatically. Founded in 2020 and backed by Y Combinator, its platform is deployed across 15 countries with customers including Unilever and Riedel.

Conifer develops compact, rare-earth-free electric powertrains using patented axial flux motor technology and ferrite magnets. Founded by ex-Apple and Lucid engineers, the company's software-driven manufacturing approach enables cost-effective, supply-chain-resilient motors for two- and four-wheel vehicles, lawn equipment, and tractors.

Danu Robotics is an Edinburgh, Scotland-based startup that builds H.E.R.O., an AI-powered robot that sorts recyclable materials using a mechanical pincer claw gripper instead of suction-based systems. Founded by Amy Ma after six years of development, the company targets the roughly $20 billion recycling-sorting market across Europe and North America, competing with suction-based rivals Glacier and RecycleEye.

Dili (YC S23) builds AI automation for compliance in construction and other physical industries. Its platform handles prevailing wage, apprenticeship, and labor compliance tracking for energy, infrastructure, datacenter, advanced manufacturing, and construction projects, and has supported over $1B in federal funding claims. The company started as an AI due-diligence copilot for deal teams before focusing on industrial compliance.

Discovered Materials (formerly Matforge, YC Spring 2026) builds swarms of AI agents that act as "AI scientists" to design candidate semiconductor materials and their synthesis routes, then validates them against real lab testing. It targets data center chip supply-chain needs including fab, advanced packaging, interconnect, and thermal interface materials. The company aims to compress 10+ year materials R&D cycles into months.

Dusty Robotics develops robotic layout systems for construction teams, including the FieldPrinter platform for translating BIM plans to jobsites.

Stanford-spinout based in Fremont, California developing metal-hydrogen batteries with 30,000-cycle life and 30-year design life for grid-scale long-duration energy storage. The company is scaling manufacturing, including operations in China, to serve utility and renewable integration customers.

Flow Computing develops Parallel Processing Unit technology to accelerate next-generation CPUs for AI, edge, cloud, and parallel computing workloads.

GreenVibe builds wireless, ultrasound-based sensors that are embedded in concrete before pouring to measure strength, temperature, humidity and density in real time. Its IoT communication hub streams the readings to a cloud platform so contractors can decide when to strip formwork, begin post-tensioning, or move to the next construction stage. Founded in Israel in 2019, the company claims up to 95% correlation with the concrete actually poured on site.

Deep-tech mining and energy startup developing proprietary laser-based drilling systems to unlock Europe's critical minerals and geothermal energy at extreme depths. Building Europe's first technology-driven mining and energy platform with plans to begin selling European-mined critical raw materials by 2029.

Harmoni is a factory orchestration platform that connects operators, machines, ERP systems, and quality data to coordinate shop-floor work for manufacturers. The company recently launched HAL, an AI system built for the front lines of manufacturing, enabling rapid deployment with less manual work and stronger process adherence.

Helix Earth Technologies is a Houston-based NASA and Rice University spinout that manufactures bolt-on HVAC retrofit devices using proprietary liquid-gas chemistry (the Helix MICRA filter) to dramatically improve the energy efficiency of existing commercial and residential heating and cooling systems. Its technology decouples humidity control from temperature management, reducing energy consumption and extending equipment lifespan.

AI-powered manufacturing platform that ships custom factory software rapidly with agents that write code and deliver a live Factory OS in 24 hours.

Hyphen is a foodservice automation platform combining robotics and AI to put culinary operations on autopilot. Their Automated Makeline assembles digital orders at 350+ meals per hour with zero errors, while CulinaryOS handles inventory, labor, and order management for restaurant operators.

Impulse Space is an in-space transportation and orbital maneuvering company based in Redondo Beach, California, building kick stages and vehicles to move satellites between orbits. Founded by former SpaceX propulsion lead Tom Mueller, it has reached unicorn status with $1.8B in total funding.

Instrumental builds an AI-powered manufacturing optimization platform for complex electronics, combining in-line camera hardware with computer-vision models that detect defects, surface root causes, and enforce quality controls across contract-manufacturing lines. Founded by two ex-Apple engineers, it is used by consumer-electronics and data-center hardware makers to improve yield and speed up failure analysis. In March 2026 it announced an investment from NVIDIA's NVentures tied to accelerating AI server and rack manufacturing.

Isembard builds AI-powered, software-driven factories (via its MasonOS platform) to reshore high-precision manufacturing for aerospace, defence, energy, and robotics industries in Europe. It uses a franchise model to convert or launch machine shops that run on its proprietary automation and AI system.

Juna AI is an industrial AI platform that develops autonomous agents for manufacturing and production optimization. Their platform orchestrates AI agents to help factories plan, steer, and improve industrial processes across scheduling, process engineering, and resource management.

Keychain is an AI-powered platform for CPG manufacturing that connects brands and retailers with a global network of over 30,000 vetted manufacturers. Its KeychainOS operating system helps manufacturers manage production cycles with AI-driven compliance, planning, and traceability modules.

LeydenJar develops and produces pure silicon anodes for energy-dense batteries, enabling 70% more energy storage while reducing CO2 emissions by 85% with 7-minute charging capability.

Liquid Death is a better-for-you beverage brand selling canned water, iced tea, and sparkling energy with a sustainability-focused, entertainment-driven consumer brand.

Premium bottled water brand offering purified spring water from protected mountain springs in Southern California, exclusively in glass bottles. Features chemical-free membrane filtration, precise mineralization with trace magnesium and Celtic sea salt, third-party lab verification accessible via QR codes, PFAS-free, plastic-free, and NSF certified for transparency and purity.

Defense technology company building unmanned defense systems and distributed manufacturing.

Mazama Energy develops superhot rock enhanced geothermal systems (EGS), using advanced drilling, reservoir engineering, and heat-harvesting technology to deliver gigawatt-scale, carbon-free power. The company's pilot site at Newberry, Oregon achieved a record 629°F in an engineered geothermal reservoir and is advancing toward commercial-scale power generation.

Molten Salt Solutions develops isotope-enrichment technology for advanced nuclear and fusion supply chains, using a proprietary chromatography and mass-spectrometry approach to enrich lithium-6 and lithium-7. The company, based in Santa Fe, New Mexico, says its platform is roughly 100x more efficient than legacy enrichment methods.

Regenerative medicine company developing stem cell-derived tissue and organ replacement therapies for liver disease using iPSC-derived platform technology, with operations in Montreal, Cambridge and Toronto

NEURA Robotics is a German company building cognitive and humanoid robots powered by embodied AI, including the 4NE-1 humanoid and the MiPA personal-assistant robot. Founded in 2019 and headquartered in Metzingen, Germany, it develops full-stack robotics that combine proprietary hardware, sensors, and AI software for industrial and service use. In June 2026 it announced a record Series C of up to $1.4B led by Tether, with Amazon, NVIDIA, and Qualcomm participating.

Neuron Industries builds the Cortex AIC, an AI-programmable industrial controller that replaces traditional PLCs, with control programming in plain English/Python, an integrated development environment, HMI, and process-data historian built into the device. The company is based in El Segundo, CA and is part of Y Combinator's Summer 2026 batch.

Noitom Robotics develops embodied intelligence technology for humanoid robots, providing high-fidelity motion capture, teleoperation systems, and multimodal data acquisition platforms used to train robot perception and locomotion. The company positions itself as a data infrastructure provider — 'a robot company that doesn't build robots' — supplying scalable training data and tooling to robot manufacturers and embodied AI model teams. It spun out of Noitom Technology, a global leader in professional motion capture.

Nominal provides the connected hardware test stack used to capture telemetry, validate systems, and ship complex hardware faster. Its software supports aerospace, defense, and industrial teams running mission-critical test and operations workflows.

Nordoon is a Palo Alto-based agentic automation platform that deploys AI operators to automate critical supply chain operations including order confirmation, three-way matching, delivery updates, and ERP data entry in manufacturing environments. Founded in 2023 by Blaz Fortuna and Tomaz Suklje, the platform connects email communications to ERP systems and integrates with SAP, Oracle, Microsoft Dynamics, and NetSuite. The company raised a Pre-Seed round in October 2024 from Silicon Gardens and Interactive Venture Partners.

NORI Robotics is a San Francisco-based startup building affordable bimanual home robots. Its flagship NORI L2 is a two-armed household robot starting at $1,288 that autonomously handles chores like loading the dishwasher, folding laundry, and cleaning, with a skill-sharing marketplace and remote-operation support. The robot is made in the US and slated to ship summer 2026.

NovoLINC develops breakthrough nanostructured thermal interface materials for AI computing, data centers, and high-power electronics. Its proprietary technology achieves 10X lower thermal resistance than conventional materials, enabling better heat dissipation for next-generation semiconductor chips and cooling critical AI infrastructure.

Parallax is building modular natural-gas turbines of about 10 MW for on-site power at AI data centers. The units use 3D-printed cores made from common alloys and fit in shipping containers. It emerged from stealth in September 2026, with prototypes planned for 2026 and customer deliveries in 2028.

Phasic Energy combines applied AI with next-generation hardware to build 3D-printed heat exchangers for demanding thermal environments, including data centers, defense, geothermal, and industrial waste-heat recovery applications. The NYC-based startup is a small team of under 10 people that recently closed a $7.5M Venture round.

Power Dynamics designs, manufactures and deploys integrated modular systems that pair sustainable energy with high-density compute — KW/MW/GW battery energy storage systems (BESS), single-phase immersion cooling for GPUs, and containerized modular data centers. The company also builds industrial heat-recovery systems that reuse waste heat from GPUs for processes like textile dyeing and food sterilization. Co-founded and led by CEO Jen Zhu Scott, with manufacturing and project deployment in Meizhou, Guangdong.

Prometheus is a Physical AI company co-founded by Jeff Bezos and Vik Bajaj building an 'artificial general engineer' — AI that can design, experiment on, and manufacture complex physical products such as jet engines, drugs, and advanced materials. The company operates out of San Francisco, London, and Zurich, recruiting researchers from OpenAI, DeepMind, and Meta. It raised a $12B round in June 2026 at a ~$41B valuation, bringing total funding above $18B.

Prox builds AI technical support agents for complex physical products such as power tools, HVAC systems, industrial heaters, EV chargers, and CNC machines. Its multimodal platform is grounded in product manuals and cited to the page, and can draw wiring schematics, share CAD models, and handle voice and video support across product pages, dealer counters, internal tools, ChatGPT, and Claude. The company serves hardware and industrial-equipment makers in powersports, agriculture, HVAC, firearms, and construction equipment.

AI-powered construction takeoff, cost estimation, and procurement platform delivering 90% faster takeoffs and 95% accuracy for subcontractors, general contractors, and developers.

South Korean AI chip company developing neural processing units (NPUs) for AI inference workloads. Offers AI accelerators, chiplets, interconnects, and software stacks for large-scale deployments.

Rebulk (formerly dScribe AI) uses computer vision and autonomous drones to track bulk inventory such as grain, sand, and gravel in real time. The platform creates 3D reconstructions from drone and fixed camera feeds to deliver precise volume and weight measurements for industrial supply chains, serving customers in agriculture and mining. Part of Y Combinator's S25 batch.

Developer of the world's first DC data centers built exclusively for solar and wind power. Using proprietary chip design and smart controllers, Rune converts stranded and curtailed renewable energy into compute power at generation sites.

Schematik is an AI-native IDE — a 'Cursor for hardware' — that turns a plain-English project description into firmware code, wiring diagrams, a component list, and step-by-step assembly instructions for Arduino, ESP32, and Raspberry Pi Pico. Generated firmware can be flashed directly to boards via PlatformIO or exported for customization. The product is built on Anthropic's Claude models.

Science Corporation is a neural engineering company developing brain-computer interface (BCI) technology to restore and enhance human vision. The company's PRIMA retinal implant uses advanced neurotechnology to treat blindness caused by conditions like age-related macular degeneration, Stargardt disease, and retinitis pigmentosa. Founded by Neuralink co-founders Max Hodak and Alan Mardinly, Science has raised $489 million and is racing to become the first BCI company with a product in market.

Sennos builds AI software for fluidics and fermentation operations, focusing on process monitoring, optimization, and bioprocess analytics.

Automation technology provider for fish processing industry using sensor fusion, edge computing, and machine learning for humane seafood processing

Sierra Space designs and builds commercial spacecraft, space station modules, and orbital infrastructure, including the Dream Chaser reusable spaceplane and components for the Orbital Reef commercial space station. The company is headquartered in Louisville, Colorado, with additional operations in Broomfield and Centennial, Colorado.

Slate Auto is a Bezos-backed EV startup building a customizable, sub-$25,000 electric pickup truck. Founded in 2022 and headquartered in Troy, Michigan, it has raised roughly $1.4 billion to date and targets the start of production by the end of 2026. The company reports over 150,000 reservations for its modular, accessory-driven truck.

Sway is a material innovation company that harnesses seaweed to create home-compostable replacements for single-use plastic packaging. Their patent-pending TPSea resin is 100% biobased and microplastic-free. Named TIME Best Invention of 2025.

Tandem is an AI-native context layer for hardware development teams, connecting design intent, requirements, CAD changes, and validation evidence in one system. Its AI generates ECO drafts, design reviews, drawings, DFM feedback, impact reports, assembly documentation, and traceability reports from real engineering activity. Customers span aerospace, medical devices, robotics, and consumer hardware, including Fluxergy, Vaxon Space, Starlight Cardiovascular, and Endiatx.

Electric vehicle manufacturer building compact city-friendly trucks starting with the MT1 model, combining utility vehicle functionality with sustainable electric power for urban and commercial use.

Terraform Industries builds the Terraformer, a modular system that uses solar power, direct air capture, and electrolysis to synthesize pipeline-grade synthetic natural gas and other fuels from CO2 and water. Founded in 2021 by former JPL engineer Casey Handmer, the Burbank, CA-based company has deployed a solar-powered pilot plant and sold pipeline-grade gas to utilities.

Topological builds physics-based foundation models for CAD topology optimization, generating manufacturable, physics-aware designs. Its flagship model, UToP-v1, understands physics, geometry, and manufacturability to produce efficient designs far faster than traditional simulation-based methods.

Tractian is a Manufacturing AI company providing industrial maintenance and reliability solutions, combining hardware, sensors, software and AI to modernize manufacturing maintenance processes as the Industrial Copilot.

Ultra is a Brooklyn-based robotics startup that leases stationary dual-arm warehouse robots called Operator (OP1) to e-commerce fulfillment operations under a robots-as-a-service model. Founded in 2024 by Jon Miller Schwartz, Max Friefeld, Chetan Parthiban, and Oliver Ortlieb, the company has deployed OP1 units across New York, Georgia, New Jersey, and Texas warehouses, packing over 500,000 orders, and partners with Physical Intelligence to power its robots with the π0.6 foundation model.

Vantora (formerly UP.Labs) is a venture studio that co-builds AI-native operating companies with Fortune 500 industrial partners such as Porsche, Alaska Airlines, and J.B. Hunt, focusing on physical AI for manufacturing, logistics, energy, and transportation. It has launched 17 ventures since 2022 and raised its first outside capital, $100M from Silversmith Capital Partners, in September 2026.

Philadelphia-based startup building battery-electric locomotive retrofits, dynamic in-motion charging infrastructure, and renewable microgrids to electrify North American freight rail without full track electrification. Founded in 2024 by CEO Daphna Langer and Alon Kessel, it has signed a paid pilot with a Class 1 railroad.

Z Modular designs and manufactures offsite modular building systems for multifamily, hospitality, and commercial construction projects.