Crypto AI Startup Jobs

TRM Labs builds blockchain intelligence software for financial institutions, crypto businesses, and public-sector investigators to detect illicit activity and support compliance workflows.

API-first stock/ETF/crypto brokerage infrastructure for developers.

Perle is an AI training data platform that combines human expertise with adaptive workflows to help companies collect, annotate, and evaluate specialized training data for generative AI, LLMs, and RLHF. Their vetted global network of domain experts provides modular solutions for data annotation, enrichment, and adversarial robustness assessment.

Rain builds stablecoin-powered card issuing and payments infrastructure, helping fintechs and global businesses launch card programs and settle transactions with stablecoins.

Anchorage Digital is an institutional crypto platform offering custody, trading, staking, and regulated banking services for digital assets.

MoonPay is a cryptocurrency payment infrastructure platform that enables users and businesses to buy, sell, and swap crypto assets through credit cards, bank transfers, and other methods.

Mesh builds crypto payments infrastructure that lets merchants and fintech platforms accept digital assets while settling instantly in stablecoins.

Story provides AI-native blockchain infrastructure for registering, licensing, and monetizing intellectual property across the internet.

Coinflow is a payment service provider that lets merchants, web3 games, and consumer apps accept traditional card payments and settle instantly using stablecoins. Its API handles global card acceptance across 170+ countries, fraud prevention, merchant underwriting, and crypto-to-USD payouts to bank accounts. Founded in 2022 and headquartered in Chicago, it raised a $25M Series A led by Pantera Capital in October 2025.

Talos provides end-to-end institutional crypto trading platform with liquidity access, automated execution, and clearing services, reaching unicorn status with $1B+ valuation.

Layer-1 blockchain purpose-built for stablecoins and real-world payments, born from Stripe's experience in global payments and Paradigm's expertise in crypto technology.

Open-access AI cloud providing fast, affordable GPU compute, serverless inference, and dedicated hosting through a decentralized marketplace, helping developers reduce AI infrastructure costs by 50-75%.

Phantom is a leading multi-chain, self-custodial crypto wallet supporting Solana, Ethereum, Bitcoin, Base, and Polygon with over 15 million monthly active users. The platform offers token swaps, staking, NFT management, and cross-chain capabilities.

Codex is building a stablecoin-native blockchain designed specifically for cross-border payments and FX, providing on-ramps, off-ramps, and fiat-to-fiat transfers with built-in compliance and identity systems. The platform operates on an Ethereum Layer 2 using Optimism's tech stack, targeting payment service providers and enterprises in emerging markets.

Fin is a New York–based payments platform built for high-value, global, and instant transactions, using stablecoins to let users and businesses move millions of dollars in seconds to other Fin users, bank accounts, or crypto rails. Founded by ex-Citadel engineers Ian Krotinsky and Aashiq Dheeraj, the company was previously known as TipLink, a Solana-based link-to-send crypto wallet. It combines crypto settlement speed with traditional-finance reliability and compliance for cross-border and enterprise payments.

LayerZero is an omnichain interoperability protocol that enables seamless cross-chain messaging and asset transfers across 50+ blockchains. It allows developers to build decentralized applications that operate natively across multiple networks.

Notabene is a regulatory-technology platform that helps crypto businesses and financial institutions comply with the FATF Travel Rule, screen counterparties, and authorize transactions before they settle. Its compliance network connects 2,300+ institutions across 100+ jurisdictions, and its Notabene Flow product extends the network into B2B stablecoin payments. The company is remote-first and headquartered in New York.

Onchain governance infrastructure platform providing protocols and tools for DAOs and blockchain projects to manage voting, delegation, and community decision-making.

Allium is an enterprise-grade blockchain data platform that provides accurate, fast, and simple blockchain data across 100+ blockchains and 1000s of schemas, delivering historical and real-time data through interactive dashboards, APIs, and custom integrations for institutions and crypto enterprises.

Fun builds payments infrastructure that moves money on and off blockchains, offering white-label deposit, withdrawal, orchestration, and checkout flows for fintech, DeFi/trading, and sports/gaming platforms. It is the sole deposit provider for Polymarket and also powers payment flows for Lighter and Aave, processing over $18B in annual volume. Founded in 2022 and previously in stealth, the company is headquartered in Midtown NYC and is opening a Singapore office.

Blockchain-based loyalty and payments platform for restaurants, letting diners earn $FLY cryptocurrency rewards at participating restaurants. Built on Coinbase's Base layer-2 protocol.

Crypto exchange infrastructure company behind Phoenix, a decentralized exchange on Solana.

Digital trust infrastructure enabling governments and enterprises to issue, verify, and manage digital identity credentials using open-source decentralized identity toolkits.

Turnkey provides secure, scalable, and programmable crypto wallet infrastructure for embedded wallets and onchain transaction automation. Built by the team that scaled Coinbase Custody past $100B in assets, it powers 50M+ embedded wallets.

M0 builds programmable stablecoin infrastructure for financial institutions, providing minting, settlement, treasury, and compliance primitives for digital dollar products.

A Layer 1 blockchain designed from the ground up for the AI era, building a planetary-scale verifiable supercomputer that concentrates the world's compute into a single blockchain.

Sphere Labs (Sphere Laboratories, Inc.) builds SpherePay, a global stablecoin payments API and dashboard that lets businesses move dollars across borders and settle in under 30 minutes across 160+ markets. The platform handles fiat/stablecoin on- and off-ramps, cross-border settlement via local banking partners, treasury and liquidity management, and local compliance. It is also developing SphereNet, its own payments network.

Building a privacy-preserving Ethereum Layer 2 with programmable privacy and client-side proofs.

A web3 gaming infrastructure platform providing wallet-as-a-service and payment rails for games.

Blockworks provides crypto market data, research, and media for digital asset markets. It operates an onchain capital markets intelligence and networking platform that connects investors and businesses, and delivers breaking news and premium insights about digital assets and web3.

Decentralized blockchain AI platform enabling collaborative AI development with secure asset control.

Universal staking protocol offering a modular coordination framework for blockchain ecosystem, enabling protocols to evolve security models and unlock new economic primitives with over $2.7B peak TVL.

Alpen Labs builds Bitcoin infrastructure and cryptography tooling, using zero-knowledge proofs to deliver a modular rollup that makes Bitcoin scalable, private, and programmable. The remote-first team of cryptographers and engineers (ex-Blockstream, Palantir, Nethermind) is building financial rails on Bitcoin, including lending and BTC yield products. Founded in 2022, it has raised $19.1M across a seed round led by Ribbit Capital and a January 2025 strategic round led by DBA and Cyber Fund.

Crypto-integrated business banking platform that uses stablecoin rails alongside traditional payment networks.

Developer of EigenLayer restaking and the EigenCloud/EigenDA stack, enabling Ethereum stakers and operators to secure new decentralized services (AVSs).

Etherealize builds institutional-grade financial infrastructure on Ethereum, providing tokenization, Ethereum-native settlement, and zero-knowledge privacy systems for traditional financial institutions. Co-founded by Ethereum researcher Danny Ryan and former Wall Street trader Vivek Raman, it positions itself as the institutional product, business development, and marketing arm of the Ethereum ecosystem.

Decentralized protocol that executes and verifies machine learning workloads across any device, unifying global compute into a single open network.

Hummingbird builds AI-enabled compliance software for financial institutions, covering customer screening, transaction monitoring, investigations, and regulatory reporting.

Global payments infrastructure company building on Bitcoin and the Lightning Network, enabling instant low-cost money movement worldwide through APIs and SDKs for fiat, stablecoin, and bitcoin transfers.

Daylight is a decentralized energy company using software, financing, and crypto-native infrastructure to accelerate home electrification. The platform helps households adopt clean energy products while coordinating distributed energy and financing workflows.

Divine Research builds an undercollateralized lending system using stablecoins on World Chain. Since launching in December 2024, it has issued over 1 million loans to 900,000+ unique borrowers without requiring collateral or credit history.

Stable Sea provides global stablecoin-to-fiat offramp infrastructure for businesses, enabling programmatic conversion of stablecoins to local currencies across 40+ countries through a unified API.

1Money is building the world's first Layer 1 blockchain protocol designed exclusively for stablecoin payments. Founded by former Binance.US CEO Brian Shroder, the network targets enterprise-grade payment use cases with the fastest and most compliant infrastructure.

Stablecoin-powered invoice and bill payment platform that helps businesses send invoices, collect payments, and move funds across bank accounts, wallets, and local rails.

Decentralized AI search network for the Web3 Internet providing personalized search experiences and helping developers build custom search functionalities

Axis Robotics builds a distributed data engine for physical AI, letting a global network of contributors generate robot training data through browser-based teleoperation and mobile collection tools. Its simulation-first stack combines large-scale pretraining data, hybrid augmentation, and corrective post-training feedback into a continuously improving loop for embodied AI models. The network claims 100,000+ contributors producing roughly 1,200 hours of simulation and 20,000 hours of real-world data monthly, with commercial partners including Booster Robotics and Geely Auto.

BLDX is an AI-powered construction management platform that creates permanent digital building identities using blockchain technology. The platform ingests and analyzes construction documents in real-time to identify risks early, helping stakeholders reduce claim costs by an average of 30% or eliminate them entirely.

Enterprise blockchain technology company building the Daml smart contract platform and Canton Network for tokenizing real-world assets, backed by Goldman Sachs, Citadel Securities and DTCC

Eco builds stablecoin infrastructure for developers and businesses, enabling programmable money movement and one-click onchain payment flows.

EZKL builds zero-knowledge machine learning (zkML) infrastructure for verifying AI model inference. Its open-source tooling compiles PyTorch, TensorFlow, and scikit-learn models into zero-knowledge circuits, proving computations ran correctly without exposing sensitive inputs or model weights. EZKL also operates a high-performance proving cluster.

Kite (formerly ZettaBlock) is building the payments and identity layer for the agent economy — a purpose-built L1 blockchain plus an Agent Passport that gives autonomous AI agents verifiable identity, delegated authority, spending limits and session-scoped permissions. Its stack includes Kite AIR (agent identity/policy rails) and Kite Chain, a settlement layer with sub-second finality and native stablecoin support. Founded by ex-Uber, Databricks, Salesforce and NEAR infrastructure engineers and based in San Francisco.

Mangrove builds a decentralized exchange with an on-chain order book and programmable liquidity for DeFi traders and market makers.

Moolaah Finance (built by Moo Research Labs, Inc. / Moolaah Protocol Ltd) is building livestock-backed credit infrastructure it calls the Biological Ledger. It normalizes real-time herd telemetry from RFID tags and GPS collars into on-chain smart contracts via its ADAPT Protocol, Biological Growth Oracle, and Proof of Steak consensus, so cooperative banks, USDA FSA, SBA, and Farm Credit lenders can price agricultural loans against current collateral condition instead of stale appraisals. The team is distributed, with some roles anchored in Wyoming and Texas.

Native is a decentralized liquidity protocol enabling seamless cross-chain token swaps and DeFi integrations. It provides infrastructure for builders to embed native token exchange functionality into wallets, dApps, and exchanges.

ORO is a human intelligence protocol that enables individuals to contribute private data to AI model training while preserving privacy through zkTLS and TEE cryptography. Users earn token rewards for their data contributions.

PrismaX is a decentralized robotics service layer that sets standards for how robots, data, and human teleoperation are deployed to advance physical AI. The platform uses token incentives to crowdsource high-quality training data and operates a decentralized teleoperations network for robotics foundation model development. It combines AI, robotics, and Web3 to address data scarcity bottlenecks in autonomous robot development.

Proof of Play builds onchain game infrastructure and consumer gaming experiences for decentralized game worlds and player-owned assets.

River Markets is a San Francisco-based prime brokerage for prediction markets, giving professional and institutional traders a single interface to route orders and aggregate liquidity across venues like Kalshi and Polymarket. The platform provides execution software, market data connectivity, a Python SDK, and risk tools for managing large cross-venue orders. Founded by ex-BlackRock and ex-Morgan Stanley quants, it launched in May 2026 and is a Y Combinator Spring 2026 company.

Decentralized open-source AGI platform backed by Founders Fund and Pantera Capital, building an open AGI network where multiple AI agents collaborate in real time to prevent single-entity AGI control.

Sling Money is a stablecoin-based global payment app that uses modern real-time payment systems, the Solana blockchain, and reserve-backed stablecoins to enable nearly instant and extremely low-cost transfers across 75+ countries, with all transfers currently fee-free.

Decentralized exchange (DEX) and DeFi platform built on TON blockchain with automated market maker functionality.

Succinct is making zero-knowledge proofs accessible to any developer through SP1, their zkVM, and decentralized prover network that enables scalable blockchain applications and cryptographic infrastructure.

Theo builds a full-stack platform that connects onchain capital to global financial markets and makes real-world assets tradable across crypto-native workflows.

Walrus is a decentralized data layer for AI and Web3 builders, designed to store large datasets, media, and application state with programmable, verifiable access on Sui.

YieldClub is a consumer crypto savings app that automates stablecoin yield strategies so users can earn real-time interest with no lockups and without needing deep crypto expertise.

Zama builds open-source fully homomorphic encryption technology and confidentiality infrastructure for blockchain and other privacy-preserving applications.